Results 101 to 110 of about 683,039 (264)

Multichannel Modified Covariance Estimator of a Single-Tone Frequency

open access: yesCybernetics and Information Technologies, 2015
The multichannel modified covariance estimator of a single-tone signal frequency is synthesized by using the maximum likelihood method. It is shown that this estimator has an advantage over the estimator averaged by multiple conventional single-channel ...
Chyrka I. D., Omelchuk I. P.
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

"Improving Small Sample Properties of the Empirical Likelihood Estimation" [PDF]

open access: yes
We propose to use a simple modification of the maximum empirical likelihood (MEL) method for estimating structural equation in econometrics. The modified estimator improves both the asymptotic bias and the mean squared error of the MEL estimator in the ...
Naoto Kunitomo
core  

Estimating the Modified Weibull Parameters in Presence of Constant-Stress Partially Accelerated Life Testing

open access: yesJournal of Statistical Theory and Applications (JSTA), 2018
Accelerated life testing is very important in life testing experiments because it saves time and cost. In this paper, assuming that the lifetime of items under use condition follows the modified Weilbull distribution, partially accelerated life tests ...
Mohamed A. W. Mahmoud   +2 more
doaj   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Contemporaneous Threshold Autoregressive Models: Estimation, Testing and Forecasting [PDF]

open access: yes
This paper proposes a contemporaneous smooth transition threshold autoregressive model (C-STAR) as a modification of the smooth transition threshold autoregressive model surveyed in Teräsvirta (1998), in which the regime weights depend on the ex ante ...
Fabio Spagnolo   +2 more
core   +3 more sources

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

open access: yesFEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz   +9 more
wiley   +1 more source

On modified skew logistic regression model and its applications

open access: yesStatistica, 2015
Here we consider a modified form of the logistic regression model useful for situations where the dependent variable is dichotomous in nature and the explanatory variables exhibit asymmetric and multimodal behaviour.
C. Satheesh Kumar, L. Manju
doaj   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

Simulation and Robust Modifications of Estimates in Branching Processes [PDF]

open access: yes, 2004
This study is focused on the comparison and modification of different estimates arising in the branching processes. Simulations of models with or without migration are put through.
Atanasov, D., Stoimenova, V., Yanev, N.
core  

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