Results 41 to 50 of about 682,094 (268)

Nonparametric confidence intervals for monotone functions

open access: yes, 2015
We study nonparametric isotonic confidence intervals for monotone functions. In Banerjee and Wellner (2001) pointwise confidence intervals, based on likelihood ratio tests for the restricted and unrestricted MLE in the current status model, are ...
Groeneboom, Piet, Jongbloed, Geurt
core   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

Using Simulation to Estimate Reliability Function for Transmuted Exponential Distribution

open access: yesJournal of Applied Science and Engineering, 2022
Several methods were used to estimate the two parameters of the transformed exponential distribution, which are the scale and the transmuted parameters, as well as its reliability function, namely, the moments method, modified moments, percentile, least ...
Makki A. Mohammed Salih   +2 more
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Estimation and Testing in One-Way ANOVA when the Errors are Skew-Normal

open access: yesRevista Colombiana de Estadística, 2015
We consider one-way analysis of variance (ANOVA) model when the error terms have skew- normal distribution. We obtain the estimators of the model parameters by using the maximum likelihood (ML) and the modified maximum likelihood (MML) methodologies (see,
NURI CELIK, BIRDAL SENOGLU, OLCAY ARSLAN
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Statistical analysis of wind speed distribution based on sixWeibull Methods for wind power evaluation in Garoua, Cameroon

open access: yesRevue des Énergies Renouvelables, 2015
Wind data analysis and accurate wind energy potential assessment are critical factors for suitable development of wind power application at a given location.
D.K. Kidmo   +3 more
doaj  

INTERVAL ESTIMATION OF WEIBULL DISTRIBUTION BASED ON MODIFIED PIVOTAL VARIABLE METHOD (MT)

open access: yesJixie qiangdu, 2023
To solve the problems of complex calculation and weak applicability of the traditional interval estimation methods such as Weibull distribution with the different parameters, a simple interval estimation method suitable to the conditions of multi ...
XUE GuangMing   +4 more
doaj  

The Modified Beta Gompertz Distribution: Theory and Applications

open access: yesMathematics, 2018
In this paper, we introduce a new continuous probability distribution with five parameters called the modified beta Gompertz distribution. It is derived from the modified beta generator proposed by Nadarajah, Teimouri and Shih (2014) and the Gompertz ...
Ibrahim Elbatal   +4 more
doaj   +1 more source

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