Results 41 to 50 of about 15,363,485 (274)

MPI-PHYLIP: parallelizing computationally intensive phylogenetic analysis routines for the analysis of large protein families. [PDF]

open access: yesPLoS ONE, 2010
Phylogenetic study of protein sequences provides unique and valuable insights into the molecular and genetic basis of important medical and epidemiological problems as well as insights about the origins and development of physiological features in ...
Alexander J Ropelewski   +2 more
doaj   +1 more source

Exercise Capacity, Physical Activity, Fatigue, and Neurocognitive Function in Adult Survivors of Childhood Acute Lymphoblastic Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Adult survivors of childhood acute lymphoblastic leukemia (ALL) are at risk of reduced exercise capacity, decreased physical activity levels, persistent fatigue, and neurocognitive deficits. The aim was to investigate exercise capacity and physical activity levels of adult survivors of childhood ALL and their associations with ...
Laura Jess   +5 more
wiley   +1 more source

On zero - inflated logarithmic series distribution and its modification

open access: yesStatistica, 2014
Here we consider a zero-inflated logarithmic series distribution (ZILSD) and study some of its properties. A modified form of ZILSD is also developed and derived several important aspects of it. The parameters of modified ZILSD are estimated by method of
C. Satheesh Kumar, A. Riyaz
doaj   +1 more source

Using Simulation to Estimate Reliability Function for Transmuted Exponential Distribution

open access: yesJournal of Applied Science and Engineering, 2022
Several methods were used to estimate the two parameters of the transformed exponential distribution, which are the scale and the transmuted parameters, as well as its reliability function, namely, the moments method, modified moments, percentile, least ...
Makki A. Mohammed Salih   +2 more
doaj   +1 more source

Identifying Patterns of Hospitalizations Among Childhood Cancer Survivors: A Population‐Based Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Childhood cancer survivors (CCSs) experience more hospitalizations than the general population. We aimed to identify distinct hospitalization patterns among Queensland CCSs and the associated characteristics. Methods Cases (aged ≤14 years) diagnosed between 1995 and 2019 while residents of Queensland were identified through the ...
Hai Pham   +7 more
wiley   +1 more source

Estimation and Testing in One-Way ANOVA when the Errors are Skew-Normal

open access: yesRevista Colombiana de Estadística, 2015
We consider one-way analysis of variance (ANOVA) model when the error terms have skew- normal distribution. We obtain the estimators of the model parameters by using the maximum likelihood (ML) and the modified maximum likelihood (MML) methodologies (see,
NURI CELIK, BIRDAL SENOGLU, OLCAY ARSLAN
doaj   +1 more source

Reliability estimation and parameter estimation for inverse Weibull distribution under different loss functions

open access: yesKuwait Journal of Science, 2021
In this paper, the classical and Bayesian estimators of the unknown parameters and reliability function of the inverse Weibull distribution are considered.
Asuman Yılmaz, Mahmut Kara
doaj   +1 more source

R.A. Fisher and the making of maximum likelihood 1912-1922

open access: yes, 1997
In 1922 R. A. Fisher introduced the method of maximum likelihood. He first presented the numerical procedure in 1912. This paper considers Fisher's changing justifications for the method, the concepts he developed around it (including likelihood ...
Aldrich, J., John Aldrich, Aldrich, John
core   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

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