Results 61 to 70 of about 105,291 (201)

A modified version of the inference function for margins and interval estimation for the bivariate Clayton copula SUR Tobit model: An simulation approach [PDF]

arXiv, 2014
This paper extends the analysis of bivariate seemingly unrelated regression (SUR) Tobit model by modeling its nonlinear dependence structure through the Clayton copula. The ability in capturing/modeling the lower tail dependence of the SUR Tobit model where some data are censored (generally, at zero point) is an additionally useful feature of the ...
arxiv  

Bacteria‐Derived Extracellular Vesicle as A “Trojan Horse” for Selective M1 Macrophage‐Targeting in A Multi‐Cellular Entanglement Environment

Advanced Functional Materials, EarlyView.
The temporary transition of macrophages from a pro‐inflammatory phenotype of macrophages (M1) to an anti‐inflammatory phenotype of macrophages (M2) is crucial for tissue repair and regeneration processes. Bacterial outer membrane vesicles (OMVs) are utilized as a “trojan horse” for specific M1 macrophage‐targeting and anti‐inflammatory drug delivery ...
Donglin Cai, Zhelun Li, Wendong Gao, Yuqing Mu, Jiaying Liu, Yufeng Zhang, Xiaohan Mei, Jingjing Quan, Lan Xiao, Yin Xiao   +9 more
wiley   +1 more source

Magnetically Guided Mechanoactive Mineralization Scaffolds for Enhanced Bone Regeneration

Advanced Functional Materials, EarlyView.
A 3D‐printed ‘rebar‐concrete’ inspired scaffold (PGS‐P@MGel) synergizes spontaneous biomineralization with magneto‐mechanical stimulation through PDA@Fe3O4‐embedded hydrogel. This dual biointerface activates Piezo1/β‐catenin/YAP mechanotransduction axis, enhancing BMSCs osteogenesis and angiogenesis simultaneously.
Xuran Guo, Zaijin Tao, Zhenzhen Dai, Yinghua Gao, Chengzhen Chu, Cunyi Fan, Shen Liu, Xin Ma, Fangchun Jin, Zhengwei You, Jia Jiang   +10 more
wiley   +1 more source

Biomimetic Co‐delivery of Lenvatinib and FePt Nanoparticles for Enhanced Ferroptosis/Apoptosis Treatment of Hepatocellular Carcinoma

Advanced Healthcare Materials, EarlyView.
This study introduces a novel HCC treatment using poly lactic‐co‐glycolic acid (PLGA) nanoparticles encased in HCC cell membranes to co‐deliver Lenvatinib and FePt nanoparticles. This approach improves treatment efficacy by enhancing ferroptosis and apoptosis.
Feichao Xuan, Xingyang Zhao, Weiran Pang, Zirong Li, Xiangyi Yin, Weizhong Xie, Xiaojun Zeng, Liming Nie, Junying Yang, Shiying Li, Puxiang Lai, Chihua Fang   +11 more
wiley   +1 more source

Precision Photothermal Therapy at Mild Temperature: NIR‐II Imaging‐Guided, H2O2‐Responsive Stealth Nanobomb

Advanced Healthcare Materials, EarlyView.
The new generation nanobomb, termed the stealth nanobomb, is fabricated through self‐assembly using a polymeric carbon monoxide carrier (PLGA(CO)), small molecule near‐infrared‐active agents (2TT‐OC46B), and phospholipid polyethylene glycol (DSPE‐mPEG2000). The stealth nanobomb can circulate in the bloodstream and specifically target pancreatic cancer,
Gongcheng Ma, Qihang Ding, Yue Wang, Zhiwei Zhang, Yuding Zhang, Hui Shi, Lintao Cai, Ping Gong, Pengfei Zhang, Zhen Cheng, Jong Seung Kim   +10 more
wiley   +1 more source

Probiotic‐Based Mineralized Living Materials to Produce Antimicrobial Yogurts

Advanced Healthcare Materials, EarlyView.
The self‐assembly and mineralization of collagen in the presence of probiotics produces hybrid living materials that hosts and protects the cells. Intra‐ and interfibrillar mineralization of collagen fibers, as occurring in bone, results, respectively, in a bulk and single‐cell protective layer of cells, that survive in simulated gastric conditions and,
Gloria B. Ramírez‐Rodríguez, Laura Sabio, Laura Cerezo‐Collado, Víctor Garcés, Jose M. Domínguez‐Vera, José M. Delgado‐López   +5 more
wiley   +1 more source

Ovarian Function Restoration with Biomimetic Scaffold Incorporating Angiogenic Molecules and Antioxidant in Chemotherapy‐Induced Perimenopausal Model

Advanced Healthcare Materials, EarlyView.
This study developed a biomimetic scaffold incorporating PDRN and melatonin to restore ovarian function in chemotherapy‐induced premature ovarian insufficiency, enhancing cell survival, folliculogenesis, and hormone normalization, while improving fertility rates and offspring in a mouse model, offering a promising strategy for ovarian function ...
Da‐Seul Kim, Dong Seok Jeong, So‐Yeon Park, Ji‐Won Jung, Jeoung Eun Lee, Jun‐Kyu Lee, Seung‐Woon Baek, Dong Ryul Lee, Dong Keun Han   +8 more
wiley   +1 more source

First Description of Discrete Stars Composing the Milk Way in Thomas Watson's Hekatompathia (1582) [PDF]

arXiv, 2003
We note that the first unambiguous description of the Milk Way as being composed of a large number of discrete stars is in Sonnet 31 of Thomas Watson's (d 1592) Hekatompathia (1582), nearly 30 years before Galileo's description. We discuss implications of this early description.
arxiv  

Lycium‐Barbarum Polysaccharide‐Loaded Dual‐Crosslinked Rigid Hydrogel Enhances Bone Healing in Diabetic Bone Defects by Scavenging Reactive Oxygen Species

Advanced Healthcare Materials, EarlyView.
A novel hydrogel (HLBP) incorporating natural polysaccharides from goji berries is developed to enhance diabetic bone defect healing. The hydrogel efficiently scavenges ROS, improves osteogenic differentiation, and promotes in vivo bone regeneration. This strategy offers a biocompatible and localized approach, overcoming the challenges of traditional ...
Wenjie Zhong, Wenao Liao, Lingcong Xu, Niezhenghao He, Ke Xu, Caiyuan Liu, Fei Wang, Wei Zhang, Jiang Hu, Haowen Cui   +9 more
wiley   +1 more source

Recipe recommendation using ingredient networks [PDF]

arXiv, 2011
The recording and sharing of cooking recipes, a human activity dating back thousands of years, naturally became an early and prominent social use of the web. The resulting online recipe collections are repositories of ingredient combinations and cooking methods whose large-scale and variety yield interesting insights about both the fundamentals of ...
arxiv