Results 111 to 120 of about 98,914 (278)

Acute Stroke Intervention In Young Patients [PDF]

, 2013
Purpose: Stroke is a disease of the elderly, however it can affect the younger patients. We present a retrospective review of our series of young patients (55 years old and younger), treated at our institution from 2007 to 2012, to assess the safety ...
Dumont, MD, Aaron S., El-Chalouhi, MD, Nohra, Gonzalez, MD, L. Fernando, Jabbour, MD, Pascal, Rosenwasser, MD, Robert, Sidhu, BS, Nimrita, Singhal, MBBS, Saurabh, Thakkar, MBBS, Vismay, Tjoumakaris, Stavropoula, MD   +8 more
core   +2 more sources

Impact of Asymptomatic Intracranial Hemorrhage on Outcome After Endovascular Stroke Treatment

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Endovascular treatment (EVT) achieves high rates of recanalization in acute large‐vessel occlusion (LVO) stroke, but functional recovery remains heterogeneous. While symptomatic intracranial hemorrhage (sICH) has been well studied, the prognostic impact of asymptomatic intracranial hemorrhage (aICH) after EVT is less certain ...
Shihai Yang, Chengsong Yue, Zhuang Li, Xiaolei Shi, Haoxuan Zhu, Jie Yang, Linyu Li, Jiaxing Song, Shitao Fan, Gaoming Li, Wenzhe Sun, Zhixian Ye, Jiacheng Huang, Dahong Yang, Jinfu Ma, Xu Xu, Zhixi Wang, Lilan Wang, Guojian Liu, Fengli Li, Changwei Guo, Li Qi, Wenjie Zi   +22 more
wiley   +1 more source

Outcome after Endovascular Treatment of Patients with Ruptured Cerebral Aneurysm over 90 Years of Age

Neurologia Medico-Chirurgica
For ruptured cerebral aneurysms over 90 years of age, the outcome and the safety after endovascular treatment are not well-known. This multicenter retrospective registry enrolled patients with ruptured cerebral aneurysms after endovascular treatment from
Fuminori SHIMIZU, Kazutaka UCHIDA, Jiro TAKEUCHI, Hiroto KAKITA, Sou SAWAMURA, Akihiro KANBARA, Yuji KITADA, Yoshinori AKIYAMA, Takashi YOSHIDA, Kiyoshi ASADA, Satoru FUJIWARA, Hirotoshi IMAMURA, Chiaki SAKAI, Manabu SHIRAKAWA, Shinichi YOSHIMURA, Nobuyuki SAKAI, Masato KASAHARA, the JR-NET4 Study Group   +17 more
doaj   +1 more source

The Utility of Health States After Stroke: A Systematic Review of the Literature [PDF]

, 2001
Background—: To perform decision analyses that include stroke as one of the possible health states, the utilities of stroke states must be determined. We reviewed the literature to obtain estimates of the utility of stroke and explored the impact of the ...
Post, P.N. (Piet), Stiggelbout, A.M. (Anne), Wakker, P.P. (Peter)   +2 more
core  

A Retrospective Cohort Study to Assess Patient and Physician Reported Outcome Measures After Decompressive Hemicraniectomy for Malignant Middle Cerebral Artery Stroke. [PDF]

, 2017
INTRODUCTION: Decompressive hemicraniectomy for malignant middle cerebral artery (MCA) infarction is known to reduce mortality. However, there are on-going concerns in terms of the quality of life in survivors. We aimed to examine the correlation between
Budhdeo, S, Chari, A, Clark, DJ, Hutchinson, PJ, Kolias, AG, Warburton, EA   +5 more
core   +1 more source

Sarilumab in Polyarticular‐Course Juvenile Idiopathic Arthritis: Dose‐Finding and One‐Year Analysis of a Phase 2b, Open‐Label, Multicenter Study

Arthritis Care &Research, Accepted Article.
Objective This study assessed sarilumab in treating patients with polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods This phase 2b, open‐label study (NCT02776735) consisted of three sequential parts (each with a core‐treatment and extension‐phase). During part 1, three doses were assessed in two weight groups (Group A/B: ≥30–60 kg/≥10–<
Fabrizio De Benedetti, Inmaculada C. Penadés, Irina Nikishina, Ivan Foeldvari, Alberto J. Spindler, Anna Kozlova, Nadina Rubio‐Pérez, Pierre Quartier, Zbigniew Żuber, Raul Barria, Daniel Clemente, Gabriel V. Cornejo, Katherine Marzan, Nancy Liu, Christine Xu, Stephen DiMartino, Angeliki Giannelou, Fei Cao‐Ghoul, Bolanle Akinlade, Lydie Baret‐Cormel   +19 more
wiley   +1 more source

SiO2‐CaOCME/Poly(Tetrahydrofuran)/Poly(Caprolactone) 3D‐Printed Scaffolds Drive Human‐Bone Marrow Stromal Cell Osteogenic Differentiation

Advanced Healthcare Materials, EarlyView.
3D printed hybrid scaffolds combining bioactive silica–calcium chemistry with elastic polymers guide human bone stem cells to form bone. The scaffolds support cell survival, organization, and invasion while releasing osteogenic ions. Together, architecture and composition drive bone‐specific gene expression, extracellular matrix organization, and ...
David R. Sory, Agathe C.M. Heyraud, Julian R. Jones, Sara M. Rankin   +3 more
wiley   +1 more source

Outcome after Endovascular Treatment of Patients with Acute Ischemic Stroke with Large Vessel Occlusion over 90 Years of Age

Neurologia Medico-Chirurgica
The effectiveness of endovascular therapy for patients aged 90 years and over (90 years) is still not well understood. We compared the patients aged 90 years with those aged 85-89 years, 80-84 years, and
Fuminori SHIMIZU, Kazutaka UCHIDA, Hiroto KAKITA, Sou SAWAMURA, Akihiro KANBARA, Yuji KITADA, Yoshinori AKIYAMA, Takashi YOSHIDA, Satoru FUJIWARA, Hirotoshi IMAMURA, Chiaki SAKAI, Manabu SHIRAKAWA, Shinichi YOSHIMURA, Nobuyuki SAKAI, the JR-NET4 Study Group   +14 more
doaj   +1 more source

One-Year Risk of Stroke after Transient Ischemic Attack or Minor Stroke [PDF]

, 2016
BACKGROUND Previous studies conducted between 1997 and 2003 estimated that the risk of stroke or an acute coronary syndrome was 12 to 20% during the first 3 months after a transient ischemic attack (TIA) or minor stroke.
Albers, Gregory W., Amarenco, Pierre, Bornstein, Natan M., Canhão, Patrícia, Caplan, Louis R., Donnan, Geoffrey A., Ferro, José M., Hennerici, Michael G., Labreuche, Julien, Lavallée, Philippa C., Molina, Carlos, org Steering Committee, T. I. A. r. e. g. i. s. t. r. y., Rothwell, Peter M., Sissani, Leila, Steg, Philippe Gabriel, Toni, Danilo, Touboul, Pierre Jean, Uchiyama, Shinichiro, Vicaut, Éric, Wong, Lawrence K. S., Školoudík, David   +20 more
core   +2 more sources

Microglial Fkbp5 Impairs Post‐Stroke Vascular Integrity and Regeneration by Promoting Yap1‐Mediated Glycolysis and Oxidative Phosphorylation

Advanced Science, EarlyView.
A post‐stroke perivascular niche of microglia characterized by low expression of M2 markers and elevated glycolysis, oxidative phosphorylation (OXPHOS), and phagocytic activity is identified, which is termed stroke‐activated vascular‐associated microglia (stroke‐VAM).
Yanan Li, Yanmei Qiu, Yunlei Yang, Yanhao Wei, Haokun Peng, Longhai Zeng, Pengcheng Li, Rentang Bi, Bo Hu   +8 more
wiley   +1 more source