Results 131 to 140 of about 32,167 (256)

Engineered 3D cultured human nasal mucosa mesenchymal stem cell derived sEVs for targeted brain‐derived neurotrophic factor delivery to enhance neurogenesis and attenuate brain damage

Interdisciplinary Medicine, EarlyView.
This study successfully developed and evaluated BDNF@RVG‐sEVs, a novel brain‐targeted nanomedicine based on hnmMSC‐derived sEVs, designed to overcome the BBB and enhance neurorestoration. By integrating RVG for enhanced brain targeting and encapsulating BDNF for potent neurorepair, our system address the key limitations of the conventional sEVs and ...
Xueting Wang, Junge Chen, Jiao Xia, Weitong Yang, Teng Ma, Tianzi Shan, Weifeng He, Gaoman Zhang, Zhuoran Xia, Weiwei Wang, Zhusheng Liu, Zhiqiang Yi, Piye Niu, Tian Chen   +13 more
wiley   +1 more source

Removal of pharmaceuticals from municipal wastewater using a powdered activated carbon‐supplemented moving bed membrane bioreactor

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKGROUND The new European Union Wastewater Directive 2024/3019 requires upgrading sewage treatment plants to achieve 80% removal of micropollutants. This study aimed to compare different Powdered Activated Carbon dosing strategies within a hybrid Moving Bed‐Membrane Bioreactor (PAC‐MB‐MBR) system, to evaluate its performance and to study the
Athanasia Iliopoulou, Petros Mastoras, Georgia Gatidou, Kallisti Skarveli, Konstantina Adamaki, Olga S Arvaniti, Maria Aloupi, Michail S Fountoulakis, Athanasios S Stasinakis   +8 more
wiley   +1 more source

Bromelain as the enzyme of the future: A global bibliometric mapping of its applications and emerging trends

Journal of the Science of Food and Agriculture, EarlyView.
Abstract INTRODUCTION Bromelain, a complex mixture of proteolytic enzymes primarily extracted from plants of the Bromeliaceae family, has gained prominence because of its broad industrial applicability, particularly in the food, pharmaceutical and cosmetic sectors.
Genésio José da Silva Neto, Tonny Cley Campos Leite, Mônica Tejo Cavalcanti, Geany Targino Sousa Pedrosa, Rerisson do Nascimento Alves, Amanda Reges de Sena, Mônica Correia Gonçalves   +6 more
wiley   +1 more source

Chain‐End Grafting of RAFT Polyelectrolyte Macroligands to Stabilize Near‐Infrared‐Emitting Gold Nanoclusters

Macromolecular Rapid Communications, EarlyView.
Surface‐functionalized gold nanoclusters (AuNCs) are synthesized in situ by chain‐end grafting of RAFT polyelectrolytes at room temperature directly in water. It leads to highly stable polymer‐AuNCs nanohybrids emitting near‐infrared photoluminescence with µs lifetimes. ABSTRACT With their photoluminescence properties, gold nanoclusters (AuNCs, d<2 nm)
Bárbara Casteleiro, Pierre Alcouffe, Fernande Da Cruz, Agnès Crépet, José Manuel Gaspar Martinho, Marie‐Thérèse Charreyre, José Paulo Sequeira Farinha, Arnaud Favier   +7 more
wiley   +1 more source

CO2‐Responsive Dual‐Charge‐Switchable Membranes for Protein Foulant Cleaning

Macromolecular Rapid Communications, EarlyView.
CO2‐responsive poly(ether sulfone) ultrafiltration membranes with dual‐charge‐switchable surfaces are prepared by incorporating an amphoteric diblock copolymer additive using the nonsolvent‐induced phase separation method. Alternating CO2 and N2 bubbling changes the solution pH around the copolymer isoelectric point and hence reversibly switches the ...
Niloofar Zamanian, Yue Zhao
wiley   +1 more source

Mass Spectrometry Insights Into Post‐Translational Modifications in Extracellular Vesicles

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are membrane‐enclosed structures secreted by virtually all living cells, serving as essential mediators of intercellular communication in both physiological and pathological processes. There is growing interest in their potential applications as biomarkers, therapeutic targets, and drug delivery systems, which ...
Dávid Virág, Krisztián Márk Karvaly, Alexandra Molnár, Mirjam Balbisi, Júlia Németh, Lilla Turiák   +5 more
wiley   +1 more source

Mass Spectrometry‐Based Extracellular Vesicle Proteomics for Biomarker Discovery

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Extracellular vesicle (EV) proteomics has emerged as a powerful platform for decoding intercellular communication and advancing biomarker discovery across human diseases. EVs carry proteins that reflect their cells of origin, offering a minimally invasive window into physiological and pathological processes.
Ya‐Juan Liu, Juan Peng, Chao Kang
wiley   +1 more source

Effects of Modified Ultrafiltration in Pediatric Cardiac Surgery.

Japanese Journal of Cardiovascular Surgery, 2001
Kazuyuki Miyamoto, Kunihiro Yonenaga, Touitsu Hirayama, Ichiro Ideta   +3 more
openaire   +3 more sources

Unspecific Molecular Adsorption (UMA) Sample Preparation Method for Bottom‐up and Whole Protein Analysis: The Foundation

PROTEOMICS, EarlyView.
ABSTRACT The protein sample preparation methods for shotgun proteomics are nowadays well‐established unlike the ones for whole protein analysis. The goal of my work has been to create a simple methodology which provides a single uncomplicated sample preparation tool for these two fields. Nowadays the bulk of proteomics work is done using detergents for
Alexandre Zougman
wiley   +1 more source

Rechargeable N‐Halamine Functionalized Ultra‐Thin PES Ultrafiltration Membranes

Journal of Polymer Science, EarlyView.
An automated 3D printer‐assisted casting platform is utilized to fabricate ultra‐thin polyethersulfone membranes with precise structural control. The integration of a custom‐synthesized, regenerable N‐halamine homopolymer imparts superior, cyclic antifouling resistance and rapid, broad‐spectrum antibacterial efficacy.
Ahmet Aydın, Fatma Demirci, Hasan Basri Kocer   +2 more
wiley   +1 more source