Results 21 to 30 of about 202,716 (219)
Vehicles, 2023 Electric vehicles (EVs) are experiencing explosive growth in public adoption, causing a major shift in research and development priorities by OEMs toward electrified powertrains.
Martin R. Kardasz, Mehrdad Kazerani
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Quantitative and modularized CRISPR/dCas9-dCpf1 dual function system in Saccharomyces cerevisiae
Frontiers in Bioengineering and Biotechnology, 2023 Introduction: Both CRISPR/dCas9 and CRISPR/dCpf1 genome editing systems have shown exciting promises in modulating yeast cell metabolic pathways. However, each system has its deficiencies to overcome.
Qing Feng +4 more
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Post-Workshop Report for Plug-N-Harvest Modular Façade Retrofit Workshop on Sustainable Places 2019
Proceedings, 2019 As part of the European Commission Horizon 2020 Plug-N-Harvest project consortium, authors hosted a 90-minute workshop to discuss issues related the modular façade retrofit development in Europe on Sustainable Places 2019 conference at Cagliari ...
Hu Du +3 more
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Air-breathing Mg-Cu/CuO fuel cell
Journal of Engineering and Applied ScienceMagnesium fuel cells deliver higher electrical power output than lithium-ion batteries and have the potential to become an economically attractive alternative power source for domestic purposes.
R. Jayakrishnan +4 more
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IEEE Open Journal of Power Electronics, 2023 Realizing an isolated three-phase Power Factor Correction (PFC) ac-dc converter as a phase-modular system, i.e., by star-connecting three single-phase PFC rectifier front-ends with individual isolated dc-dc converter stages generating a common dc output ...
David Menzi +3 more
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Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Journal of CheminformaticsAutoencoders are frequently used to embed molecules for training of downstream deep learning models. However, evaluation of the chemical information quality in the latent spaces is lacking and the model architectures are often arbitrarily chosen ...
Marie Oestreich +2 more
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Factory-Built Housing in Indonesia: Current Practice and Future Challenges
Jurnal Teknik Sipil, 2005 Recent earthquake and tsunami in Aceh and North Sumatra has left Indonesia big responsibility in fulfilling housing need for people who lost their homes after this calamity.
Andi Asiz, Dicky R. Munaf
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