Results 41 to 50 of about 12,619 (240)
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
A Helly theorem in weakly modular space
, 1996 The d-convex sets in a metric space are those subsets which include the metric interval between any two of its elements. Weak modularity is a certain interval property for triples of points.
Bandelt, Hans-Jürgen, Chepoi, Victor
core +1 more source
Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
FEBS Open Bio, EarlyView.An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
Amenability, Countable Equivalence Relations, and Their Full Groups [PDF]
, 2008 This thesis consists of an introduction and four independent chapters. In Chapter 1, we study homeomorphism groups of metrizable compactifications of the natural numbers. Those groups can be represented as almost zero-dimensional Polishable subgroups
Tsankov, Todor Dimitrov
core +1 more source
Why human connection is the true metric of research success
FEBS Open Bio, EarlyView.Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source
Modular feature selection using relative importance factors
, 2004 Feature selection plays an important role in finding relevant or irrelevant features in classification. Genetic algorithms (GAs) have been used as conventional methods for classifiers to adaptively evolve solutions for classification problems.
Li, P, Guan, SU, Zhu, F
core +1 more source
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source
Modular spaces and topologies on modular spaces
, 2023 Yüksek Lisans TeziTezimiz dört bölümden oluşmaktadır. Birinci bölümde metrik uzaylar ve modüler metrik ile ilgili genel bilgi verilerek matematikteki tarihsel gelişimi verilmiştir.
Haşimoğlu, Firdevs
core
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background and Objectives Multiple sclerosis (MS) exhibits racially disparate rates of disease progression. Black people with MS (B‐PwMS) experience a more severe disease course than non‐Hispanic White people with MS (NHW‐PwMS). Here we investigated structural and functional connectivity as well as structure–function decoupling in the ...
Emilio Cipriano +11 more
wiley +1 more source