Results 81 to 90 of about 21,194 (310)

A Modular Computation Method for Flow Distribution Characteristics of Air in Duct System of Indirect Cooling Refrigerator

open access: yesZhileng xuebao, 2015
A modular computation method for predicting the flow distribution characteristics in duct system of indirect cooling refrigerator was presented.
Wan Bowen, Zhao Dan, Ding Guoliang
doaj  

Implementation of RSA Signatures on GPU and CPU Architectures

open access: yesIEEE Access, 2020
This paper reports a constant-time CPU and GPU software implementation of the RSA exponentiation by using algorithms that offer a first-line defense against timing and cache attacks.
Eduardo Ochoa-Jimenez   +3 more
doaj   +1 more source

On the use of observation equivalence in synthesis abstraction

open access: yes, 2011
In a previous paper we introduced the notion of synthesis abstraction, which allows efficient compositional synthesis of maximally permissive supervisors for large-scale systems of composed finite-state automata.
Simon Ware   +7 more
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Automatic Generation of Locomotion Patterns for Soft Modular Reconfigurable Robots

open access: yesApplied Sciences, 2019
In recent years, soft modular robots have become popular among researchers with the development of soft robotics. However, the absence of a visual 3D simulation platform for soft modular robots hold back the development of the field.
Xin Sui   +5 more
doaj   +1 more source

Hierarchical State Machines as Modular Horn Clauses [PDF]

open access: yesElectronic Proceedings in Theoretical Computer Science, 2016
In model based development, embedded systems are modeled using a mix of dataflow formalism, that capture the flow of computation, and hierarchical state machines, that capture the modal behavior of the system.
Pierre-Loïc Garoche   +2 more
doaj   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

open access: yesMolecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski   +12 more
wiley   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Computing Modular Invariants of p-groups

open access: yesJournal of Symbolic Computation, 2002
The authors study the action of a \(p\)-group \(G\) on a polynomial ring over a field of characteristic~\(p\) by linear transformations of the variables. The main goal is to find methods for the symbolic computation of generators for the ring of invariants under such an action.
R. James Shank, David L. Wehlau
openaire   +2 more sources

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