Results 91 to 100 of about 46,611 (262)

Integrated PANoptosis Profiling Identifies Immunosuppressive Subtypes and a Prognostic Signature With Functional Validation of MLKL in Glioblastoma

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian   +6 more
wiley   +1 more source

Carbon Reduction Potential of Modular Bathroom Systems in the A1–A3 Life-Cycle Stages

open access: yesBuildings
Efforts to reduce greenhouse gas (GHG) emissions across various sectors are on-going to overcome the global climate crisis induced by global warming.
Sang-Heon Lee   +3 more
doaj   +1 more source

Asymmetric addition of Grignard reagents to ketones: culmination of the ligand-mediated methodology allows modular construction of chiral tertiary alcohols. [PDF]

open access: yesChem Sci, 2022
Monasterolo C   +9 more
europepmc   +1 more source

Simulation of modular building construction [PDF]

open access: yes2008 Winter Simulation Conference, 2008
Osama M. Mohsen   +4 more
openaire   +1 more source

CSF Cytokine Network Organization Predicts Progression Independent of Relapse and MRI Activity in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Progression independent of relapse activity is a major determinant of long‐term disability in multiple sclerosis, but its immunopathologic basis remains incompletely understood. We investigated whether relapse‐independent progression in radiologically stable relapsing–remitting multiple sclerosis is associated with distinct ...
Antonio Bruno   +19 more
wiley   +1 more source

Modular reactors: What can we learn from modular industrial plants and off site construction research

open access: yesNuclear Engineering and Technology
New modular factory-built methodologies implemented in the construction and industrial plant industries may bring down costs for modular reactors. A factory-built environment brings about benefits such as; improved equipment, tools, quality, shift ...
Paul Wrigley   +5 more
doaj   +1 more source

Addressing Economic Insecurities Can Improve Patient‐Reported Outcomes in Lupus

open access: yesArthritis Care &Research, EarlyView.
Objective Economic insecurities, such as food, housing, transportation, and financial challenges, are modifiable risk factors and influence patient‐reported outcomes (PROs) in systemic lupus erythematosus (SLE). We examined the following: (1) associations between economic insecurities and PROs, and (2) the impact of screening and addressing economic ...
Jay Patel   +8 more
wiley   +1 more source

Modular momentum: assessing the efficacy of modular construction in alleviating the UK housing crisis

open access: yesDiscover Applied Sciences
This manuscript critically evaluates the potential of modular construction as a viable remedy to the ongoing housing crisis in the UK. In light of the escalating construction costs and the long-standing lack of productivity gains in the residential ...
Luana Parisi, Sohrab Donyavi
doaj   +1 more source

Integrating Patient‐Reported Quality Measures in Systemic Lupus Erythematosus: Development of the American College of Rheumatology Implementation Guide

open access: yesArthritis Care &Research, EarlyView.
Objective To support high‐quality, patient‐centered care for systemic lupus erythematosus (SLE), the American College of Rheumatology (ACR) developed evidence‐based measures incorporating clinical and patient‐reported outcome measures (PROMs). Using the Consolidated Framework for Implementation Research (CFIR), we conducted semistructured interviews ...
Catherine Nasrallah   +13 more
wiley   +1 more source

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