Results 81 to 90 of about 3,315,782 (302)

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Modular conception and construction

open access: yes, 2020
The factsheet gives a high-level definition of designing solar thermal systems for district heating. In addition, modules are introduced which can be used for modelling systems and finally, methods for estimating energy yield and costs of systems are described.
Lukas Feierl, Maria Moser, Hannes Poier
openaire   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Modelling construction business performance [PDF]

open access: yes, 2008
Searching academic databases for records on ‘business failure’, ‘business distress’ or ‘bankruptcy’\ud yields a large body of studies on qualitative, empirical, theoretical and simulation aspects.

core  

Numerical and Experimental Study on Modular-Based Timber Structures [PDF]

open access: yes, 2019
Building with prefabricated light-frame volume modules is a prevalent and innovative construction method for low and mid-rise timber buildings.
Kua, Le   +7 more
core   +1 more source

Off-site modular construction and design in nuclear power: A systematic literature review

open access: yes, 2021
Off-Site Modular Construction (OSMC) research has been a burgeoning research area over the past two decades due to low productivity of traditional construction methods. Some large Gen 3 reactors may employ an on-site assembly area similar to shipbuilding
Robertson, D.   +7 more
core   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

Construction planning workbench [PDF]

open access: yes, 2004
This report is an attempt to present the current state of product and process modelling in the building industry in general, and in construction planning and scheduling in particular.

core  

A Framework to Improve Modular Construction Manufacturing Production Line Performance [PDF]

open access: yes, 2017
This thesis describes the implementation of a production line assessment framework to help shift off-site modular construction manufacturing (MCM) from a conventional construction approach toward true manufacturing.
Zhang, Youyi
core   +1 more source

Application information redundancy to improve reliability the arithmetic unit computing elements bimodule arithmetic

open access: yesНаука. Инновации. Технологии, 2022
The traditional way of building modular devices constructive postulates the need to include in the modular device bulky non-modular unit that is running a series-parallel op-erations of modular arithmetic.
Viljan Mavlutinovich Amerbaev   +3 more
doaj  

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