Results 61 to 70 of about 61,713 (311)
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Modular synthesis of discrete controllers [PDF]
, 2007 This paper presents supervisory control theory in a process-algebraic setting, and proposes a way of synthesising modular supervisors that guarantee nonblocking.
Reeves, Steve +7 more
core +1 more source
Advantages and barriers of modular construction method in constructing buildings [PDF]
, 2023 This study aims to investigate the advantages of and barriers to the modular construction method that could facilitate leveraging of this method in practice by effectively overcoming barriers in the process.
Chen, C, Chuwei Chen
core +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
BuildingsConstruction professionals work in silos and use traditional design and construction methods. The growing demand for rapidly built and high-quality construction is making off-site manufacturing mainstream.
Marie-Laure Filion +3 more
doaj +1 more source
Applied Sciences, 2020 Quality control is essential to a successful modular construction project and should be enhanced throughout the project from design to construction and installation.
Huimin Li +4 more
doaj +1 more source
A generic framework for context-sensitive analysis of modular programs [PDF]
, 2004 Context-sensitive analysis provides information which is potentially more accurate than that provided by context-free analysis. Such information can then be applied in order to validate/debug the program and/or to specialize the program obtaining ...
Stuckey, P.J. +14 more
core +2 more sources
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Multi-Performance Characterization of a Modular Wooden House
Energies, 2023 Although not a new concept, modular construction has been the target of increasing interest and investment in recent years. Modular wood construction systems have economic and environmental advantages, as wood is a natural and locally available raw ...
João M. P. Q. Delgado +7 more
doaj +1 more source
Modular conception and construction
, 2020 The factsheet gives a high-level definition of designing solar thermal systems for district heating. In addition, modules are introduced which can be used for modelling systems and finally, methods for estimating energy yield and costs of systems are described.
Lukas Feierl, Maria Moser, Hannes Poier
openaire +1 more source