Results 51 to 60 of about 46,611 (262)

Modular conception and construction

, 2020
The factsheet gives a high-level definition of designing solar thermal systems for district heating. In addition, modules are introduced which can be used for modelling systems and finally, methods for estimating energy yield and costs of systems are described.
Lukas Feierl, Maria Moser, Hannes Poier
openaire   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Constructing modular separating invariants

Journal of Algebra, 2009
Consider a finite dimensional representation \(V\) of a group \(G\) over a field \(F\). The induced action on the dual \(V^*\) extends to an action by algebra automorphisms on the symmetric algebra \(F[V]:=S(V^*)\). The elements of \(F[V]\) represent polynomial functions on \(V\). An invariant polynomial \(f\in F[V]^G\) is constant on \(G\)-orbits. For
openaire   +5 more sources

Modular brain construction [PDF]

Science, 2016
Neurodevelopment The mammalian cerebellum looks complex on the surface, with a stereotypical pattern of lobules and fissures. Although its subregions all seem to use similar types of cells, tracts coming from elsewhere in the brain target distinct portions of the cerebellum, suggesting that surface formations reflect functional zones.
openaire   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Modular Construction in the Digital Age: A Systematic Review on Smart and Sustainable Innovations

Buildings
Modular construction provides numerous benefits over traditional methods, especially when combined with digital technologies, offering a faster, safer, leaner, and more sustainable construction environment.
Diogo F. R. Parracho, Mohamed Nour El-Din, Iraj Esmaeili, Sara S. Freitas, Leonardo Rodrigues, João Poças Martins, Helena Corvacho, João M. P. Q. Delgado, Ana Sofia Guimarães   +8 more
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Inspection of intermodular connection locations for multistory modular buildings

Measurement + Control
Modular construction is a method of construction that involves prefabricating modular indoor spaces in a factory and then assembling them at the construction site.
Jae Sang Moon, Wonseok Seo, Hyeunguk Ahn, Jinyoung Kim   +3 more
doaj   +1 more source