Results 41 to 50 of about 14,033,253 (353)
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Modular product design and customization [PDF]
, 2009 Organised by: Cranfield UniversityThe paper deals with modular design architecture and its capabilities for easy and fast customization in products. The basic principles of modularity are mentioned and the most known methodologies and tools for modular
Chryssolouris, G., Pandremenos, J.
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Developing modular product family using GeMoCURE within an SME
, 2010 Companies adopt the strategy of producing variety of products to be competitive and responsive to market. Product variation is becoming an important factor in companies' ability to accurately meet customer requirements.
Yan, Xiu-Tian, Stewart, Barry
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Cell type-specific delivery by modular envelope design
Nature Communications, 2023 The delivery of genetic cargo remains one of the largest obstacles to the successful translation of experimental therapies, in large part due to the absence of targetable delivery vectors.
Daniel Strebinger +5 more
semanticscholar +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
EnergiesThermal insulation materials used in power and industrial systems must maintain high performance under extreme environmental conditions. Among such materials, aerogel and basalt fiber are widely applied due to their low thermal conductivity and ease of ...
Irina Akhmetova +9 more
doaj +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Realising the open virtual commissioning of modular automation systems [PDF]
, 2011 To address the challenges in the automotive industry posed by the need to rapidly manufacture more product variants, and the resultant need for more adaptable production systems, radical changes are now required in the way in which such systems are ...
Jain, Atul +11 more
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