Results 61 to 70 of about 12,232,847 (349)

Preliminary structural design method for modular wing

Hangkong gongcheng jinzhan
Aircraft modular design can increase the types of missions and reduce costs. In the initial stage of wing modular structure design，the unclearness of wingtip deformation limits the ability to assess the contribution differences of structural stiffness ...
FAN Fulei, LI Yi, CHEN Chunying, JIA Zhaohu   +3 more
doaj   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Integrating Design for Manufacturing and Assembly Principles in Modular Home Construction: A Comprehensive Framework for Enhanced Efficiency and Sustainability

Buildings
The growing demand for sustainable and efficient construction practices has led to an increased interest in modular construction, with design for manufacture and assembly emerging as a pivotal approach.
Sadaf Montazeri, Nicole Odo, Syed Abdul Wasey Naqvi, Zhen Lei   +3 more
doaj   +1 more source

Microfluidic electro‐viscoelastic manipulation of extracellular vesicles

FEBS Open Bio, EarlyView.
The electro‐viscoelastic manipulation as a potential method for separation of particles based on size. The particles introduced as a sheath flow migrate to the channel center under the influence of simultaneously applied electric field and pressure driven flow.
Seyedamirhosein Abdorahimzadeh, Éva Bozó, Zikrullah Bölükkaya, Artem Zhyvolozhnyi, Anatoliy Samoylenko, Henrikki Liimatainen, Seppo J. Vainio, Caglar Elbuken   +7 more
wiley   +1 more source

Modular forms and ellipsoidal T-designs

The Ramanujan Journal, 2022
In recent work, Miezaki introduced the notion of a $spherical$ $T$-d$esign$ in $\mathbb{R}^2$, where $T$ is a potentially infinite set. As an example, he offered the $\mathbb{Z}^2$-lattice points with fixed integer norm (a.k.a. shells). These shells are $maximal$ spherical $T$-designs, where $T=\mathbb{Z}^+\setminus 4\mathbb{Z}^+$.
openaire   +2 more sources

Characterization of WAC interactions with R2TP and TTT chaperone complexes linking glucose and glutamine availability to mTORC1 activity

FEBS Open Bio, EarlyView.
TTT and R2TP chaperone complexes are required for the assembly and activation of mTORC1. WAC directly interacts with components of TTT, R2TP, and mTORC1, and these interactions are affected by the availability of glucose and glutamine, correlating with changes in mTORC1 activity.
Sofía Cabezudo, Natalia Cuervo, Carmen García‐Martín, Andrés López‐Perrote, Clara Reglero, Adrián Maqueda‐Real, Ana González‐Corpas, Marina Serna, Diego Megías, Alejo Efeyan, Solip Park, Oscar Llorca   +11 more
wiley   +1 more source

The cochaperone BAG3 promotes the stabilization of p53 under heat stress conditions

FEBS Open Bio, EarlyView.
Under heat stress, BAG3 translocates to the nucleus and forms a complex with Hsp70 and p53, thereby promoting p53 stabilization and enhancing its transcriptional activity. These findings suggest that BAG3 functions as a cochaperone that supports p53‐mediated stress responses in cooperation with Hsp70.
Ngoc Nguyen Thi Minh, Esther Lee, Soo‐A Kim   +2 more
wiley   +1 more source

Teaching Python with team‐based learning: using cloud‐based notebooks for interactive coding education

FEBS Open Bio, EarlyView.
This study presents a novel approach to teaching Python and bioinformatics using team‐based learning and cloud‐hosted notebooks. By integrating interactive coding into biomedical education, the method improves accessibility, student engagement, and confidence—especially for those without a computing background.
Nuno S. Osório, Leonardo D. Garma
wiley   +1 more source

Implementing Immersive Worlds for Metaverse-Based Participatory Design through Photogrammetry and Blockchain

ISPRS International Journal of Geo-Information
This paper explores participatory design methods for the interconnection of digital recording techniques, like digital photogrammetry and Gaussian splatting, with emerging domains such as the metaverse and blockchain technology.
Nikolai Abramov, Havana Lankegowda, Shunwei Liu, Luigi Barazzetti, Carlo Beltracchi, Pierpaolo Ruttico   +5 more
doaj   +1 more source

Modulinio projektavimo taikymo paslaugoms problematika / Problematic of service modularisation

Mokslas: Lietuvos Ateitis, 2019
Maintaining a competitive edge in today’s markets with short product life cycles and competitors quickly copying commercial success ideas is a significant challenge.
Ilona Skačkauskienė, Jurga Vestertė
doaj   +1 more source