Results 71 to 80 of about 12,907,560 (338)
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Modularization method based on creation of new layout structure
Nihon Kikai Gakkai ronbunshu, 2017 This paper describes a modularization method based on the creation of a new layout structure by combining topology optimization using beam elements and clustering analysis.
Hidekazu NISHIGAKI, Yasuo ASAGA
doaj +1 more source
A modular design of molecular qubits to implement universal quantum gates. [PDF]
Nat Commun, 2016 The physical implementation of quantum information processing relies on individual modules—qubits—and operations that modify such modules either individually or in groups—quantum gates.
Ferrando-Soria J +11 more
europepmc +2 more sources
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
An experience of modularity through design [PDF]
, 2001 We aim to utilise the experiences of a marine industry-based design team to determine the need for research into a modular design methodology in an industrial environment.
Duffy, Alex H.B. +4 more
core
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
A Method for Design of Modular Reconfigurable Machine Tools
Machines, 2017 Presented in this paper is a method for the design of modular reconfigurable machine tools (MRMTs). An MRMT is capable of using a minimal number of modules through reconfiguration to perform the required machining tasks for a family of parts.
Zhengyi Xu +3 more
doaj +1 more source
Supporting the automated generation of modular product line safety cases [PDF]
, 2015 The effective reuse of design assets in safety-critical Software Product Lines (SPL) would require the reuse of safety analyses of those assets in the variant contexts of certification of products derived from the SPL.
Braga, Rosana T.V. +5 more
core +1 more source
Design and Analysis of a High-Gain Step-Up/Down Modular DC–DC Converter with Continuous Input Current and Decreased Voltage Stress on Power Switches and Switched-Capacitors [PDF]
, 2021 Maysam Abbasi +3 more
openalex +1 more source
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source