Results 31 to 40 of about 167,831,130 (242)

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Level lowering for half-integral weight modular forms [PDF]

open access: yes, 2010
In this paper we provide a level lowering result for half-integral weight modular forms. The main ingredients are the Shimura map from half-integral weight modular forms to integral weight modular forms along with a level lowering result for integral ...
Brown, Jim, Li, Yingkun
core  

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

On Hecke L-functions attached to half-integral weight modular forms [PDF]

open access: yesJournal of Number Theory, 2018
We investigate non-vanishing properties of $L(f,s)$ on the real line, when $f$ is a Hecke eigenform of half-integral weight $k+{1\over 2}$ on $Γ_0(4).$
CHOIE, YOUNG JU, Kohnen, Winfried
openaire   +4 more sources

Diagonalising modular forms of half-integral weight

open access: yesJournal of Number Theory, 1992
The authors continue their study [J. Number Theory 34, 210-224 (1990; Zbl 0704.11013)] on cusp forms of half-integral weight on the groups \(\Gamma_ 0(4M)\) for odd squarefree \(M\). They introduce operators \(C(4)\) and \(C(p^ 2)\) for the primes \(p\mid M\) which are analogous to the operators \(C(p)\) for cusp forms of even weight introduced by ...
Manickam, M.   +2 more
openaire   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu   +21 more
wiley   +1 more source

Shimura Images of A Family of Half-Integral Weight Modular Forms [PDF]

open access: yes, 2013
In 1973, Shimura introduced a family of maps between modular forms of half-integral weight and modular forms of even integral weight. We will give explicit formulas for the images of two different classes of modular forms under these maps. In contrast to
Brown, Kenneth Allan
core   +1 more source

Cycle integrals and rational period functions for Γ0+(2) and Γ0+(3)

open access: yesOpen Mathematics
For p∈{2,3}p\in \left\{2,3\right\} and an even integer kk, let Wk−2−(p){W}_{k-2}^{-}\left(p) be the space of period polynomials of weight k−2k-2 on Γ0+(p){\Gamma }_{0}^{+}\left(p) with eigenvalue −1-1 under the Fricke involution.
Choi SoYoung   +2 more
doaj   +1 more source

Deep Learning Pose Estimation for Phenotyping of Co‐Occurring Hyperkinetic Movement Disorders

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore whether routine outpatient video combined with deep learning‐based pose estimation and clinically interpretable kinematic features can support multi‐label phenotyping of co‐occurring hyperkinetic movement disorders (HMDs).
Laura Cif   +17 more
wiley   +1 more source

Integrated PANoptosis Profiling Identifies Immunosuppressive Subtypes and a Prognostic Signature With Functional Validation of MLKL in Glioblastoma

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian   +6 more
wiley   +1 more source

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