Results 31 to 40 of about 3,734 (243)

Fuzzy Isometry and Standard Modular Structures in Modular Fuzzy Metric Spaces

Muthanna Journal of Pure Science
This paper investigates the relationship between modular metric spaces and modular fuzzy metric spaces by introducing and studying the concept of the standard modular fuzzy metric space.
Mohammed Jawad Kadhim
doaj   +1 more source

Multivalued Fixed Point Results for Two Families of Mappings in Modular-Like Metric Spaces with Applications

Complexity, 2020
The aim of this research work is to find out some results in fixed point theory for a pair of families of multivalued mappings fulfilling a new type of U-contractions in modular-like metric spaces.
Tahair Rasham, Abdullah Shoaib, Choonkil Park, Manuel de la Sen, Hassen Aydi, Jung Rye Lee   +5 more
doaj   +1 more source

Some Extensions of Fixed Point Results over Quasi-JS-Spaces

Journal of Function Spaces, 2016
We introduce the notion of quasi-JS-metric space. After defining the basic topological properties of quasi-JS-metric space, we investigate fixed point of certain mapping in the frame of complete quasi-JS-metric space.
Maha Noorwali, Hamed H. Alsulami, Erdal Karapınar   +2 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

From fuzzy metric spaces to modular metric spaces: a fixed point approach

The Journal of Nonlinear Sciences and Applications, 2017
Summary: We propose an intuitive theorem which uses some concepts of auxiliary functions for establishing existence and uniqueness of the fixed point of a self-mapping. First we work in the setting of fuzzy metric spaces in the sense of George and Veeramani, then we deduce some consequences in modular metric spaces. Finally, a sample homotopy result is
Tchier, Fairouz, Vetro, Calogero, Vetro, Francesca   +2 more
openaire   +3 more sources

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Some common fixed point theorems in generalized modular metric spaces with applications

Scientific African
In this paper, we extend the notion of weakly commuting mappings results in modular metric spaces to setting of modular ωG-metric spaces and prove the existence of unique common fixed point of three pairs of weakly commuting self-maps in modular ωG ...
Godwin Amechi Okeke, Daniel Francis
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source