Results 51 to 60 of about 59,080 (274)

Generalized Fuzzy Torus and its Modular Properties [PDF]

open access: yes, 2013
We consider a generalization of the basic fuzzy torus to a fuzzy torus with non-trivial modular parameter, based on a finite matrix algebra. We discuss the modular properties of this fuzzy torus, and compute the matrix Laplacian for a scalar field.
Schreivogl, Paul, Steinacker, Harold
core   +5 more sources

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Some Fixed Point Theorems on Compact Modular Metric Spaces

open access: yesProceedings of the Institute of Mathematics and Mechanics,National Academy of Sciences of Azerbaijan, 2020
Summary: In this article, we prove some fixed point theorems for contractive mappings in compact modular metric spaces. Then we illustrate our main theorem with an example. The application of the obtained result is also discussed.
Ozkan, Kubra, Gurdal, Utku, Mutlu, Ali
openaire   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

On multiplicative modular metric spaces of Kaplan et al.: corrections and clarifications

open access: yesFixed Point Theory and Algorithms for Sciences and Engineering
Kaplan et al. (J. Inequal. Appl. 2025:54, 2025) introduced the notion of multiplicative modular metric spaces, motivated by the framework of multiplicative metric spaces (Özavşar and Cevikel in J. Eng. Technol. Appl. Sci.
Satit Saejung
doaj   +1 more source

Chern-Simons Quantization of (2+1)-Anti-De Sitter Gravity on a Torus [PDF]

open access: yes, 1994
Chern-Simons formulation of 2+1 dimensional Einstein gravity with a negative cosmological constant is investigated when the spacetime has the topology $ R\times T^{2}$. The physical phase space is shown to be a direct product of two sub-phase spaces each
Carlip S   +11 more
core   +2 more sources

From fuzzy metric spaces to modular metric spaces: a fixed point approach

open access: yesThe Journal of Nonlinear Sciences and Applications, 2017
Summary: We propose an intuitive theorem which uses some concepts of auxiliary functions for establishing existence and uniqueness of the fixed point of a self-mapping. First we work in the setting of fuzzy metric spaces in the sense of George and Veeramani, then we deduce some consequences in modular metric spaces. Finally, a sample homotopy result is
Tchier, Fairouz   +2 more
openaire   +3 more sources

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Cop and robber game and hyperbolicity

open access: yes, 2014
In this note, we prove that all cop-win graphs G in the game in which the robber and the cop move at different speeds s and s' with s'0, this establishes a new - game-theoretical - characterization of Gromov hyperbolicity.
Chalopin, Jérémie   +3 more
core   +3 more sources

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

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