Results 91 to 100 of about 229,327 (286)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

On finite dimensional Nichols algebras of diagonal type

Bulletin of Mathematical Sciences, 2017
This is a survey on Nichols algebras of diagonal type with finite dimension, or more generally with arithmetic root system. The knowledge of these algebras is the cornerstone of the classification program of pointed Hopf algebras with finite dimension ...
Nicolás Andruskiewitsch, Iván Angiono
doaj   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Vertex operator algebras, Higgs branches, and modular differential equations

Journal of High Energy Physics, 2018
Every four-dimensional N=2 $$ \mathcal{N}=2 $$ superconformal field theory comes equipped with an intricate algebraic invariant, the associated vertex operator algebra.
Christopher Beem, Leonardo Rastelli
doaj   +1 more source

Sensing form - finger gaiting as key to tactile object exploration - a data glove analysis of a prototypical daily task

Journal of NeuroEngineering and Rehabilitation, 2020
Background Motor hand skill and associated dexterity is important for meeting the challenges of daily activity and an important resource post-stroke. In this context, the present study investigated the finger movements of right-handed subjects during ...
Werner Krammer, John H. Missimer, Simon Habegger, Manuela Pastore-Wapp, Roland Wiest, Bruno J. Weder   +5 more
doaj   +1 more source

Modular Representation Theory and Commutative Banach Algebras

Memoirs of the American Mathematical Society
In a recent paper of Benson and Symonds, a new invariant was introduced for modular representations of a finite group. An interpretation was given as a spectral radius with respect to a Banach algebra completion of the representation ring. Our purpose here is to take these notions further, and investigate the structure of the resulting Banach algebras.
openaire   +2 more sources

The Transfer in the Invariant Theory of Modular Permutation Representations II [PDF]

Canadian Mathematical Bulletin, 2001
AbstractIn this note we show that the image of the transfer for permutation representations of finite groups is generated by the transfers of special monomials. This leads to a description of the image of the transfer of the alternating groups. We also determine the height of these ideals.
openaire   +3 more sources

Remote Monitoring in Myasthenia Gravis: Exploring Symptom Variability

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is a rare, autoimmune disorder characterized by fluctuating muscle weakness and potential life‐threatening crises. While continuous specialized care is essential, access barriers often delay timely interventions. To address this, we developed MyaLink, a telemedical platform for MG patients.
Maike Stein, Maximilian Mönch, Meret Herdick, Frauke Stascheit, Sarah Hoffmann, Hannah Preßler, Philipp Mergenthaler, Carla Dusemund, Paolo Doksani, Haoqi Sun, Pushpa Narayanaswami, Andreas Meisel, Lea Gerischer, Sophie Lehnerer   +13 more
wiley   +1 more source

Proatomic modular ortholattices: Representation and equational theory

, 2015
We study modular ortholattices in the variety generated by the finite dimensional ones from an equational and geometric point of view. We relate this to coordinatization results.
Herrmann, Christian, Roddy, Michael S.
openaire   +2 more sources