Results 71 to 80 of about 229,775 (283)
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Permutation complexes and modular representation theory
Journal of Algebra, 1991 Let \(G\) be a finite group and \(R\) be a commutative ring with identity. The author calls a complex \(X_ *\) of permutation \(RG\)-modules a permutation complex if for each subgroup \(H\leq G\) the graded submodule of \(H\)-fixed points of \(X_ *\) is a subcomplex of \(X_ *\).
openaire +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Modular Representation Theory of Affine and Cyclotomic Yokonuma-Hecke Algebras [PDF]
Algebras and Representation Theory, 2019 To appear in Algebras and Representation ...
Weideng Cui, Jinkui Wan
openaire +2 more sources
Circuit complexity of knot states in Chern-Simons theory
Journal of High Energy Physics, 2019 We compute an upper bound on the circuit complexity of quantum states in 3d Chern-Simons theory corresponding to certain classes of knots. Specifically, we deal with states in the torus Hilbert space of Chern-Simons that are the knot complements on the 3-
Giancarlo Camilo +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Multi-Interval Subfactors and Modularity¶of Representations in Conformal Field Theory [PDF]
Communications in Mathematical Physics, 2001 We describe the structure of the inclusions of factors A(E) contained in A(E')' associated with multi-intervals E of R for a local irreducible net A of von Neumann algebras on the real line satisfying the split property and Haag duality. In particular, if the net is conformal and the subfactor has finite index, the inclusion associated with two ...
Kawahigashi Y., LONGO, ROBERTO, Muger M.
openaire +5 more sources
Universal sectors of two-dimensional Carrollian CFTs
Journal of High Energy PhysicsWe revisit modular invariance in two-dimensional Carrollian conformal field theories from a geometric perspective. Focusing on the characters of the induced and highest-weight representations of the theory, we show that there are regions of parameter ...
Ankit Aggarwal +5 more
doaj +1 more source