Results 71 to 80 of about 13,576 (266)
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Seven Properties of Self-Organization in the Human Brain
Big Data and Cognitive Computing, 2020 The principle of self-organization has acquired a fundamental significance in the newly emerging field of computational philosophy. Self-organizing systems have been described in various domains in science and philosophy including physics, neuroscience ...
Birgitta Dresp-Langley
doaj +1 more source
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
On the representation theory of modular Hecke algebras
Journal of Algebra, 1992 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Department of Mathematics, University of Florida, Gainesville, Florida, U.S.A. ( host institution ) +1 more
openaire +3 more sources
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source
Universal sectors of two-dimensional Carrollian CFTs
Journal of High Energy PhysicsWe revisit modular invariance in two-dimensional Carrollian conformal field theories from a geometric perspective. Focusing on the characters of the induced and highest-weight representations of the theory, we show that there are regions of parameter ...
Ankit Aggarwal +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso +5 more
wiley +1 more source
On fusing matrices associated with conformal boundary conditions
Journal of High Energy PhysicsIn the context of rational conformal field theories (RCFT) we look at the fusing matrices that arise when a topological defect is attached to a conformal boundary condition. We call such junctions open topological defects.
Anatoly Konechny, Vasileios Vergioglou
doaj +1 more source
Circuit complexity of knot states in Chern-Simons theory
Journal of High Energy Physics, 2019 We compute an upper bound on the circuit complexity of quantum states in 3d Chern-Simons theory corresponding to certain classes of knots. Specifically, we deal with states in the torus Hilbert space of Chern-Simons that are the knot complements on the 3-
Giancarlo Camilo +3 more
doaj +1 more source