Results 41 to 50 of about 59,450 (262)

To the cusp and back: resurgent analysis for modular graph functions

open access: yesJournal of High Energy Physics, 2022
Modular graph functions arise in the calculation of the low-energy expansion of closed-string scattering amplitudes. For toroidal world-sheets, they are SL(2, ℤ)-invariant functions of the torus complex structure that have to be integrated over the ...
Daniele Dorigoni   +2 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Modular flow of excited states

open access: yesJournal of High Energy Physics, 2021
We develop new techniques for studying the modular and the relative modular flows of general excited states. We show that the class of states obtained by acting on the vacuum (or any cyclic and separating state) with invertible operators from the algebra
Nima Lashkari   +2 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

New generalizations of Modular spaces

open access: yesHacettepe Journal of Mathematics and Statistics, 2020
In the present paper, we introduce the concept of $\mathcal{F}$-modular, which is a generalization of the modular notion. Moreover, we introduce a $K_p$-modular and $K$-modular, and then compare these concepts together. Finally, we give a characterization of $\mathcal{F}$-modulars.
openaire   +3 more sources

Fixed Point Theorems for a New Class of Mappings in Modular Spaces Endowed with a Graph

open access: yesAbstract and Applied Analysis, 2020
In this paper, we discuss a class of mappings more general than ρ-nonexpansive mapping defined on a modular space endowed with a graph. In our investigation, we prove the existence of fixed point results of these mappings.
Nour-eddine El Harmouchi   +2 more
doaj   +1 more source

Generalized modular fractal spaces and fixed point theorems

open access: yesAdvances in Difference Equations, 2021
In this article, we introduce a new concept of Hausdorff distance through generalized modular metric on nonempty compact subsets and study some topological properties of it.
Alireza Alihajimohammad, Reza Saadati
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Stability of an additive-quadratic functional equation in modular spaces

open access: yesOpen Mathematics
Using the direct method, we prove the Hyers-Ulam-Rassias stability of the following functional equation: ϕ(x+y,z+w)+ϕ(x−y,z−w)−2ϕ(x,z)−2ϕ(x,w)=0\phi \left(x+y,z+w)+\phi \left(x-y,z-w)-2\phi \left(x,z)-2\phi \left(x,w)=0 in ρ\rho -complete convex modular ...
Baza Abderrahman   +3 more
doaj   +1 more source

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