Results 51 to 60 of about 4,267,338 (256)

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

Convergence of Implicit Iterative Processes for Semigroups of Nonlinear Operators Acting in Regular Modular Spaces

open access: yesMathematics
This paper focuses on one-parameter semigroups of ρ-nonexpansive mappings Tt:C→C, where C is a subset of a modular space Xρ, the parameter t ranges over [0,+∞), and ρ is a convex modular with the Fatou property. The common fixed points of such semigroups
Wojciech M. Kozlowski
doaj   +1 more source

To the cusp and back: resurgent analysis for modular graph functions

open access: yesJournal of High Energy Physics, 2022
Modular graph functions arise in the calculation of the low-energy expansion of closed-string scattering amplitudes. For toroidal world-sheets, they are SL(2, ℤ)-invariant functions of the torus complex structure that have to be integrated over the ...
Daniele Dorigoni   +2 more
doaj   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Modular Space Stations [PDF]

open access: yes, 1971
The NASA Space Station Program has recently undergone substantial changes, brought about by the future availability of the Space Shuttle as an earth-to-orbit transportation system.
Ellsworth, Charles R., Allen, Leon B.
core  

Modular flow of excited states

open access: yesJournal of High Energy Physics, 2021
We develop new techniques for studying the modular and the relative modular flows of general excited states. We show that the class of states obtained by acting on the vacuum (or any cyclic and separating state) with invertible operators from the algebra
Nima Lashkari   +2 more
doaj   +1 more source

Remark on a Fixed-Point Theorem in the Lebesgue Spaces of Variable Integrability Lp(·)

open access: yesMathematics, 2022
In a personal communication, Prof. Domínguez Benavides noted that a fixed-point theorem for modular nonexpansive mappings in Lp(·)(Ω) obtained under the assumptions p+1. Therefore, the conclusion is well known.
Mohamed A. Khamsi, Osvaldo D. Méndez
doaj   +1 more source

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

open access: yesFEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

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