Results 71 to 80 of about 470,676 (223)

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Analysis of Caputo-Type Non-Linear Fractional Differential Equations and Their Ulam–Hyers Stability

Fractal and Fractional
This study presents two novel frameworks, termed a quasi-modular b-metric space and a non-Archimedean quasi-modular b-metric space, and various topological properties are provided.
Ekber Girgin, Abdurrahman Büyükkaya, Neslihan Kaplan Kuru, Mudasir Younis, Mahpeyker Öztürk   +4 more
doaj   +1 more source

New generalizations of Modular spaces

Hacettepe Journal of Mathematics and Statistics, 2020
In the present paper, we introduce the concept of $\mathcal{F}$-modular, which is a generalization of the modular notion. Moreover, we introduce a $K_p$-modular and $K$-modular, and then compare these concepts together. Finally, we give a characterization of $\mathcal{F}$-modulars.
openaire   +3 more sources

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Best approximation in b-modular spaces

مجلة بغداد للعلوم
In this paper, some basic notions and facts in the b-modular space similar to those in the modular spaces as a type of generalization are given.  For example, concepts of convergence, best approximate, uniformly convexity etc.
Hiba Adel Jabbar , Samira Naji Kadhim , Salwa Salman Abed   +2 more
doaj   +1 more source

Linear manifolds in the moduli space of one-forms

, 2007
We study closures of GL_2(R)-orbits on the total space of the Hodge bundle over the moduli space of curves under the assumption that they are algebraic manifolds.
Moeller, Martin
core   +2 more sources

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Metastring theory and modular space-time [PDF]

Journal of High Energy Physics, 2015
String theory is canonically accompanied with a space-time interpretation which determines S-matrix-like observables, and connects to the standard physics at low energies in the guise of local effective field theory. Recently, we have introduced a reformulation of string theory which does not rely on an {\it a priori} space-time interpretation or a pre-
Freidel, Laurent, Leigh, Robert, Minic, Djordje   +2 more
openaire   +2 more sources

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source