Results 61 to 70 of about 213,906 (295)

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

A phase-shifting anterior-posterior network organizes global phase relations.

open access: yesPLoS ONE
Prior research has identified a variety of task-dependent networks that form through inter-regional phase-locking of oscillatory activity that are neural correlates of specific behaviors.
Melisa Menceloglu   +2 more
doaj   +1 more source

Modular Markovian Logic [PDF]

open access: yes, 2011
We introduce Modular Markovian Logic (MML) for compositional continuous-time and continuous-space Markov processes. MML combines operators specific to stochastic logics with operators reflecting the modular structure of the models, similar to those used by spatial and separation logics.
Cardelli L., Larsen K.G., Mardare R.
openaire   +3 more sources

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Modularity and anti-modularity in networks with arbitrary degree distribution

open access: yesBiology Direct, 2010
Background Much work in systems biology, but also in the analysis of social network and communication and transport infrastructure, involves an in-depth analysis of local and global properties of those networks, and how these properties relate to the ...
Adami Christoph, Hintze Arend
doaj   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

PREVENTIVE MAINTENANCE SYSTEM DENGAN MODULARITY DESIGN SEBAGAI SOLUSI PENURUNAN BIAYA MAINTAINANCE (Studi Kasus di Perusahaan Tepung Ikan)

open access: yesJurnal Teknik Industri, 2005
Mofularity design has been applied in many European countries, especially in industrial assembling and manufacturing. Modularity design cause manufacture process and assembly process easier and cheaper.
Julianingsih Julianingsih   +1 more
doaj  

Spectral characterization of hierarchical network modularity and limits of modularity detection.

open access: yesPLoS ONE, 2013
Many real world networks are reported to have hierarchically modular organization. However, there exists no algorithm-independent metric to characterize hierarchical modularity in a complex system.
Somwrita Sarkar   +2 more
doaj   +1 more source

Revisiting the modularity of modular polyketide synthases [PDF]

open access: yesCurrent Opinion in Chemical Biology, 2009
Modularity is a highly sought after feature in engineering design. A modular catalyst is a multi-component system whose parts can be predictably interchanged for functional flexibility and variety. Nearly two decades after the discovery of the first modular polyketide synthase (PKS), we critically assess PKS modularity in the face of a growing body of ...
Chaitan, Khosla   +2 more
openaire   +2 more sources

Structure–Function Decoupling of the Sensorimotor and Default Mode Networks in Black Americans With MS

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Multiple sclerosis (MS) exhibits racially disparate rates of disease progression. Black people with MS (B‐PwMS) experience a more severe disease course than non‐Hispanic White people with MS (NHW‐PwMS). Here we investigated structural and functional connectivity as well as structure–function decoupling in the ...
Emilio Cipriano   +11 more
wiley   +1 more source

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