Results 41 to 50 of about 76,981 (315)

Modularity and anti-modularity in networks with arbitrary degree distribution

open access: yesBiology Direct, 2010
Background Much work in systems biology, but also in the analysis of social network and communication and transport infrastructure, involves an in-depth analysis of local and global properties of those networks, and how these properties relate to the ...
Adami Christoph, Hintze Arend
doaj   +1 more source

Climate change in reclamation landscapes – Adaptation between module and modularity

open access: yesAgathón, 2023
Modern drainage of wetlands has produced landscapes that are expressions of a productive view of natural space. These landscapes result from a profound environmental transformation driven by economic, social, health, and cultural reasons.
Carla Brisotto   +3 more
doaj   +1 more source

Modular implicits [PDF]

open access: yesElectronic Proceedings in Theoretical Computer Science, 2015
We present modular implicits, an extension to the OCaml language for ad-hoc polymorphism inspired by Scala implicits and modular type classes. Modular implicits are based on type-directed implicit module parameters, and elaborate straightforwardly into OCaml's first-class functors.
White, Leo   +2 more
openaire   +3 more sources

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

A phase-shifting anterior-posterior network organizes global phase relations.

open access: yesPLoS ONE
Prior research has identified a variety of task-dependent networks that form through inter-regional phase-locking of oscillatory activity that are neural correlates of specific behaviors.
Melisa Menceloglu   +2 more
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Mechanisms of Change: A Population-Based Perspective on the Roles of Modularity and Pleiotropy in Diversification

open access: yesFrontiers in Ecology and Evolution, 2020
Developmental modularity has long been viewed as a hierarchical organization that facilitates evolution through modification or reuse of preexisting modules.
James J. Lewis, Steven M. Van Belleghem
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

PREVENTIVE MAINTENANCE SYSTEM DENGAN MODULARITY DESIGN SEBAGAI SOLUSI PENURUNAN BIAYA MAINTAINANCE (Studi Kasus di Perusahaan Tepung Ikan)

open access: yesJurnal Teknik Industri, 2005
Mofularity design has been applied in many European countries, especially in industrial assembling and manufacturing. Modularity design cause manufacture process and assembly process easier and cheaper.
Julianingsih Julianingsih   +1 more
doaj  

Spectral characterization of hierarchical network modularity and limits of modularity detection.

open access: yesPLoS ONE, 2013
Many real world networks are reported to have hierarchically modular organization. However, there exists no algorithm-independent metric to characterize hierarchical modularity in a complex system.
Somwrita Sarkar   +2 more
doaj   +1 more source

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