Results 301 to 310 of about 2,950,352 (332)

NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao, Shikuan Din, Zhengkang Fu, Qian Sun, Xiwei Zhu, Yuxin Wei, Huan Qu, Xinyi Zhang, Jiaxuan Liu, Chuhua Fu, Qianxue Chen   +10 more
wiley   +1 more source

Systemic T Cell Receptor Profiling Reveals Adaptive Immune Activation and Potential Immune Signatures of Diagnosis and Brain Atrophy in Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy is increasingly associated with immune dysregulation and inflammation. The T cell receptor (TCR), a key mediator of adaptive immunity, shows repertoire alterations in various immune‐mediated diseases. The unique TCR sequence serves as a molecular barcode for T cells, and clonal expansion accompanied by reduced overall TCR ...
Yong‐Won Shin, Sang Bin Hong, Yong Woo Shin, Inpyeong Hwang, Jaeseong Oh, Jihyeon Choi, Narae Kim, Jangsup Moon, Keun‐Hwa Jung, Kyung‐Il Park, Ki‐Young Jung, Kon Chu, Sang Kun Lee   +12 more
wiley   +1 more source

Endogenous Bioelectrical Modulation by REAC Metabolic Optimization-IBZ Modulates SIRT1, PPAR-γ, and Metabolic Signaling Pathways in Human Fibroblasts. [PDF]

Cells
Cruciani S, Fontani V, Rinaldi A, Rinaldi S, Maioli M.   +4 more
europepmc   +1 more source

Regulation of Synaptic Plasticity and Adaptive Convergence Under Rhythmic Stimulation of an In Vitro Hippocampal Neuronal Network of Cultured Cells. [PDF]

Biosensors (Basel)
Sun S, Jiang L, Liu Y, Shang L, Lu C, Li S, Zhang K, Wang M, Cai X, Luo J.   +9 more
europepmc   +1 more source

Covert underwater communication through cepstrum modulation mimicking Pseudorca crassidens whistles using machine learning. [PDF]

Sci Rep
Bilal M, Zuberi HH, Jaffar A, Riaz W, Khan MA, Alharbi A, Miyajan A, Liu S.   +7 more
europepmc   +1 more source

Enhanced Loran System Demodulation for Complex Receive Environments: A Novel Matched Correlation Method Integrating Notch Filtering and Pattern Modulation. [PDF]

Sensors (Basel)
Wang X, Yan B, Jin T, Li Y, Li S, Liu S.
europepmc   +1 more source

Patient Perception of Vocal Tremor Severity and its Relationship to Acoustic Voice Outcomes: An Exploratory Study. [PDF]

Tremor Other Hyperkinet Mov (N Y)
Borders JC, Gartling G, Hary E, Amin MR, Troche MS, Barkmeier-Kraemer J, Branski RC.   +6 more
europepmc   +1 more source

Ultrafast Laser Direct Writing of Diffraction Gratings in PVA/AA Photopolymer with Tunable Phase Modulation Mechanisms. [PDF]

Polymers (Basel)
Bernabeu AP, Bravo JC, Sirvent-Verdú JJ, Nieto-Rodríguez B, Puerto D, Gallego S.   +5 more
europepmc   +1 more source

Electrically tunable strong coupling in a hybrid-2D excitonic metasurface for optical modulation. [PDF]

Light Sci Appl
Hoekstra T, van de Groep J.
europepmc   +1 more source