Results 51 to 60 of about 160,468 (296)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Optimum Mode-Switching-Assisted Constant-Power Single- and Multicarrier Adaptive Modulation
, 2003 A set of optimum mode-switching levels is derived for a generic constant-power adaptive-modulation scheme based on a closed-form expression of the average bit error ratio (BER) and the average bits-per-symbol (BPS) throughput of the adaptive-modulation ...
Choi, B.J., Hanzo, L.
core +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Deep learning‐based digital signal modulation identification under different multipath channels
IET Communications, 2021 Deep learning (DL) has been applied to digital signal modulation identification (DSMI) due to its powerful feature learning ability. However, most of the existing DL‐based DSMI methods are limited to specific experimental scene relating to the additive ...
Jiawen Zhang +5 more
doaj +1 more source
Top-Down Inference in the Auditory System: Potential Roles for Corticofugal Projections
Frontiers in Neural Circuits, 2021 It has become widely accepted that humans use contextual information to infer the meaning of ambiguous acoustic signals. In speech, for example, high-level semantic, syntactic, or lexical information shape our understanding of a phoneme buried in noise ...
Alexander Asilador +4 more
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
LMMSE channel estimation for OFDM systems with channel correlation function selection
IET Communications, 2021 In the linear minimum mean square error (LMMSE) estimation for orthogonal frequency division multiplexing (OFDM) systems, the channel correlation function (CCF) is required. Some methods have been proposed to calculate the CCF.
Kai Mei +5 more
doaj +1 more source
FEBS Letters, EarlyView.Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana +3 more
wiley +1 more source
Simulation and Emulation Approach for the Performance Evaluation of Adaptive Modulation and Coding Scheme in Mobile WiMAX Network [PDF]
, 2012 WiMAX is the IEEE 802.16e standard-based wireless technology, provides Broadband Wireless Access (BWA) for Metropolitan Area Networks (MAN). Being the wireless channels are precious and limited, adapting the appropriate modulation and coding scheme (MCS)
Shwetha, D. +3 more
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