Results 131 to 140 of about 191,998 (317)

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

A Radar Jamming Method Based on Time Domain Coding Metasurface Intrapulse and Interpulse Coding Optimization

open access: yesLeida xuebao
Time Domain Coding Metasurface (TDCM) is an emerging technology enabling dynamic modulation of electromagnetic waves. In response to the control characteristics of this technology, this paper presents a radar jamming method based on TDCM intrapulse and ...
Heng XU   +7 more
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Coded Modulation Assisted Radial Basis Function Aided Turbo Equalisation for Dispersive Rayleigh Fading Channels [PDF]

open access: yes, 2004
In this contribution a range of Coded Modulation (CM) assisted Radial Basis Function (RBF) based Turbo Equalisation (TEQ) schemes are investigated when communicating over dispersive Rayleigh fading channels.
Yee, M. S., Ng, S. X., Hanzo, L.
core  

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Pulse Intensity Coding Phase-Sensitive OTDR With Mismatched Filtering

open access: yesIEEE Photonics Journal
Optical pulse coding phase-sensitive optical time-domain reflectometry ($\Phi$-OTDR) sends a series of pulses into the sensing fiber to enhance signal-to-noise ratio (SNR). And the spatial resolution is determined by the subpulse duration.
Yaning Xie   +5 more
doaj   +1 more source

Turbo-Coded Adaptive Modulation Versus Space-Time Trellis Codes for Transmission over Dispersive Channels [PDF]

open access: yes, 2004
Decision feedback equalizer (DFE)-aided turbocoded wideband adaptive quadrature amplitude modulation (AQAM) is proposed, which is capable of combating the temporal channel quality variation of fading channels. A procedure is suggested for determining the
Liew, T.H., Wong, C.H., Hanzo, L.
core  

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

Joint design of twin-antenna assisted space-time multilevel sphere packing aided coded modulation [PDF]

open access: yes, 2006
A new multilevel coding (MLC) scheme invoking sphere packing (SP) modulation is proposed, where the SP arrangement is jointly designed with a space time block code (STBC) for the sake of attaining an additional space diversity gain.
Alamri, O., Tee, R.Y.S., Hanzo, L.
core  

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