Results 111 to 120 of about 764,488 (297)
Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
Molecular Oncology, EarlyView.The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
Inflammation-Responsive Hydrogel Spray for Synergistic Prevention of Traumatic Heterotopic Ossification via Dual-Homeostatic Modulation Strategy. [PDF]
Adv Sci (Weinh), 2023 Yang J +11 more
europepmc +1 more source
Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
Improvement of space vector modulation strategy of two-stage matrix converter
Gong-kuang zidonghua, 2013 In view of problems that space vector pulse width modulation strategy of two-stage matrix converter has high control complexity and cannot adjust input power factor of the two-stage matrix converter, a scheme of indirect space vector modulation strategy ...
DANG Cun-lu +2 more
doaj
A Rational Design of α-Helix-Shaped Peptides Employing the Hydrogen-Bond Surrogate Approach: A Modulation Strategy for Ras-RasGRF1 Interaction in Neuropsychiatric Disorders. [PDF]
Pharmaceuticals (Basel), 2021 Gulotta MR +3 more
europepmc +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
IEEE AccessHigh-Frequency Link inverters (HFLIs) have attracted significant research attention owing to their compact design, high power density, and high efficiency.
Asif Ali +4 more
doaj +1 more source
Gong-kuang zidonghua, 2015 In view of problem of unbalanced output power of each H-bridge for staircase modulation of cascaded multilevel inverter, a power balance control strategy for staircase modulation of adjusting pulse switching angle was proposed, which realized power ...
YE Manyuan, HUANG Kaifeng
doaj +1 more source
Constructing practical Fuzzy Extractors using QIM [PDF]
, 2007 Fuzzy extractors are a powerful tool to extract randomness from noisy data. A fuzzy extractor can extract randomness only if the source data is discrete while in practice source data is continuous.
Buhan, Ileana +3 more
core +2 more sources