Results 121 to 130 of about 9,256,063 (344)
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
机车电传动, 2019 In the traction drive system of rail transit, the output voltage of inverters contains many low-order harmonic components. Low-order harmonic has a negative impact on the temperature rise and loss of traction motor.
Di SHEN +3 more
doaj
IEEE AccessHigh-Frequency Link inverters (HFLIs) have attracted significant research attention owing to their compact design, high power density, and high efficiency.
Asif Ali +4 more
doaj +1 more source
Research on Hybrid Modulation Strategy for Three-level LLC Converter
Kongzhi Yu Xinxi Jishu, 2021 It adopts a single light-load fixed-frequency modulation or full-voltage range frequency conversion strategy for three-level LLC converter, which cannot take into account the widely output gain and good soft switching characteristics.This paper proposes ...
LIU Gengbo +5 more
doaj
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Non-reciprocal Optical Mirrors Based on Spatio-Temporal Modulation
, 2017 The recent surge of interest in temporal modulation schemes to induce magnet-free non-reciprocity has inspired several exciting opportunities for photonic technology. Here, we investigate a scheme to realize free-space isolators and highly non-reciprocal
Alu, Andrea +2 more
core +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
A Rational Design of α-Helix-Shaped Peptides Employing the Hydrogen-Bond Surrogate Approach: A Modulation Strategy for Ras-RasGRF1 Interaction in Neuropsychiatric Disorders. [PDF]
Pharmaceuticals (Basel), 2021 Gulotta MR +3 more
europepmc +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Improvement of space vector modulation strategy of two-stage matrix converter
Gong-kuang zidonghua, 2013 In view of problems that space vector pulse width modulation strategy of two-stage matrix converter has high control complexity and cannot adjust input power factor of the two-stage matrix converter, a scheme of indirect space vector modulation strategy ...
DANG Cun-lu +2 more
doaj