Results 111 to 120 of about 233,212 (303)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Rake Receiver Detection of Adaptive Modulation Aided CDMA over Frequency Selective Channels

open access: yes, 2001
A closed form Bit Error Ratio (BER) formula is derived for a fixed-mode Quadrature Amplitude Modulation (QAM) scheme employing Rake receivers and receiver antenna diversity.
Choi, B.J., Hanzo, L.
core  

The wavelength dependence of the modulation transfer function of the atmosphere. [PDF]

open access: yes, 1972
An apparatus was designed and constructed to measure the modulation transfer function of the atmospheric medium as a function of wavelength of light. The modulation transfer function (MTF) in this case was considered to be the ratio of the modulation ...
Mackin, Jere Gene
core  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Zoom Auxiliary Imaging Lens Design for a Modulation Transfer Function Test System

open access: yesPhotonics
In this paper, we propose a zoom auxiliary imaging lens based on the four-component mechanical zoom method for a modulation transfer function (MTF) test system. The auxiliary imaging lenses of the current MTF test system typically use fixed-focus optical
Yicheng Sheng   +5 more
doaj   +1 more source

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