Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Simulation Analysis on the Performance of a Circular-Edge Technique in Measurements of the Modulation Transfer Function. [PDF]
Maruyama S.
europepmc +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Enhancing Applicability of Reversible UV Thermochromic Offset Inks: Edge Quality Parameters and Thermochromic Printing System Modulation Transfer Function. [PDF]
Jakopčević Z +4 more
europepmc +1 more source
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Assessment of subjective image quality, contrast to noise ratio and modulation transfer function in the middle ear using a novel full body cone beam computed tomography device. [PDF]
Heikkinen AK +5 more
europepmc +1 more source
Rake Receiver Detection of Adaptive Modulation Aided CDMA over Frequency Selective Channels
A closed form Bit Error Ratio (BER) formula is derived for a fixed-mode Quadrature Amplitude Modulation (QAM) scheme employing Rake receivers and receiver antenna diversity.
Choi, B.J., Hanzo, L.
core
The wavelength dependence of the modulation transfer function of the atmosphere. [PDF]
An apparatus was designed and constructed to measure the modulation transfer function of the atmospheric medium as a function of wavelength of light. The modulation transfer function (MTF) in this case was considered to be the ratio of the modulation ...
Mackin, Jere Gene
core
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Zoom Auxiliary Imaging Lens Design for a Modulation Transfer Function Test System
In this paper, we propose a zoom auxiliary imaging lens based on the four-component mechanical zoom method for a modulation transfer function (MTF) test system. The auxiliary imaging lenses of the current MTF test system typically use fixed-focus optical
Yicheng Sheng +5 more
doaj +1 more source

