Results 131 to 140 of about 233,212 (303)

QUALITY ASSESSMENT OF MULTIFOCAL DIFFRACTIVE LENS IMAGES

open access: yesПриборы и методы измерений, 2015
The method of trifocal diffractive lens images quality assessment in the presence of the background illumination is proposed. The background component with nonuniform intensity distribution is modeled.
V. G. Kolobrodov   +2 more
doaj  

Evaluation of the modulation transfer function of a high energy X-ray tomograph

open access: yes, 2015
The modulation transfer function of a high energy computed tomography scanner is studied experimentally using the steel ball to estimate the performance of the system.
Mamyrbaev, Talgat Askarbekovich
core  

Accuracy and uncertainty in random speckle modulation transfer function measurement of infrared focal plane arrays

open access: yes, 2016
This paper expands upon a previously reported random speckle technique for measuring the modulation transfer function of midwave infrared focal plane arrays by considering a number of factors that impact the accuracy of the estimated modulation transfer ...
Jacobs, Eddie L.   +2 more
core   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Modulation transfer function and quantum efficiency in thin semiconductor photodetectors

open access: yes, 2002
© 2002 Institution of Engineering and TechnologyFor the first time, the correct equation for quantum efficiency, and hence modulation transfer function (MTF) in a semiconductor of finite thickness, is reported.
Abbott, D.
core   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Applications of the Complex Modulation Transfer Function on SEA-systems

open access: yes, 1999
The SEA coupling and dissipation loss factors are determined in-situ from Complex Modulation Transfer Functions, CMTF:s, based on measured impulse-responses.
Lund University., Lundberg, Karl-Ola,
core   +1 more source

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