Results 51 to 60 of about 215,562 (263)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Enhancing Accuracy and Precision in Omni-Angle Edge-Based Modulation Transfer Function Measurements

IEEE Access
The modulation transfer function (MTF) quantitatively describes the ability of an optical or imaging system to reproduce contrast at various spatial frequencies. The ISO 12233 edge-based method adopted diagonal MTF measurement for sampled imaging systems
Kenichiro Masaoka
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Empirical Quantification of Topobathymetric Lidar System Resolution Using Modulation Transfer Function

Earth and Space Science
Topobathymetric scanning lidar deployed on unmanned aircraft systems is a powerful tool for high‐resolution mapping of the dynamic interface between topography and bathymetry.
K. W. Sacca, J. P. Thayer
doaj   +1 more source

The Early Aging Temporal Processing: Evidence from Temporal Modulation Transfer Function with Background Noise

Auditory and Vestibular Research
Background and Aim: Temporal processing deficits are reported to contribute to speech perception difficulties in noise. However, traditional temporal resolution tasks, which are often conducted in quiet conditions, may not always reflect a noticeable ...
Aditaya Narayana Singh, Prajwal Kumar Eranna, Jayashree S Bhat   +2 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

A contralateral eye study comparing apodized diffrative and full diffrative lenses: wavefront analysis and distance and near uncorrected visual acuity

Clinics, 2009
PURPOSE: To evaluate intraindividual visual acuity, wavefront errors and modulation transfer functions in patients implanted with two diffractive multifocal intraocular lenses.
Marcony Rodrigues de Santhiago, Marcelo Vieira Netto, Jackson Barreto Jr, Beatriz de Abreu Fiuza Gomes, Arthur Schaefer, Newton Kara-Junior   +5 more
doaj   +1 more source

Modulation Transfer Function Obtained from Image Structures [PDF]

, 1989
A new and relatively simple method for edge gradient analysis (EGA) has been developed to determine the modulation transfer function (MTF) of photogrammetrical systems. The MTF can be calculated as the ratio of the amplitude of those frequencies present in the original edge to the amplitude of the same frequency in the scanned edge image.
Lei, Fang, Tiziani, Hans J.
openaire   +2 more sources