Results 51 to 60 of about 233,212 (303)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Development and Testing of a Compact Autorefractor Based on Double-Pass Imaging

open access: yesSensors, 2022
Autorefraction is an objective way to determine the refractive error of the eye, without the need for feedback by the patient or a well-educated practitioner.
Linus Emmerich   +4 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Initial On-Orbit Modulation Transfer Function Performance Analysis for Geostationary Ocean Color Imager [PDF]

open access: yesJournal of Astronomy and Space Sciences, 2012
The world’s first geostationary ocean color imager (GOCI) is a three-mirror anastigmat optical system 140 mm in diameter. Designed for 500 m ground sampling distance, this paper deals with on-orbit modulation transfer function (MTF)measurement and ...
Eunsong Oh   +4 more
doaj   +1 more source

Analysis of voltage effect on holographic gratings by modulation transfer function [PDF]

open access: yes, 2011
The experimental data allow us to determine the imaging quality of holographic gratings with photosensitive film using organic material based on a polyvinyl alcohol matrix doped with potassium dichromate and nickel (II) chloride hexahydrate.
ROSANGELA COROMOTO FONTANILLA URDANETA   +3 more
core  

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Evaluation of phase-locking to parameterized speech envelopes

open access: yesFrontiers in Neurology, 2022
Humans rely on the temporal processing ability of the auditory system to perceive speech during everyday communication. The temporal envelope of speech is essential for speech perception, particularly envelope modulations below 20 Hz.
Wouter David   +2 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Lunar-edge based on-orbit modulation transfer function (MTF) measurement

open access: yes, 2017
Modulation transfer function (MTF) is an important parameter for image quality evaluation of on-orbit optical image systems. Various methods have been proposed to determine the MTF of an imaging system which are based on images containing point, pulse ...
Hongwei yi   +5 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

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