Results 61 to 70 of about 215,562 (263)

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Wavefront analysis and modulation transfer function of three multifocal intraocular lenses

Indian Journal of Ophthalmology, 2010
Purpose: To evaluate wavefront performance and modulation transfer function (MTF) in the human eye after the implantation of diffractive or refractive multifocal intraocular lenses (IOLs). Materials and Methods: This was a prospective, interventional,
Santhiago Marcony, Netto Marcelo, Barreto Jackson, Gomes Beatriz, Schaefer Arthur, Kara-Junior Newton   +5 more
doaj  

Effect of Radiation and Gravity Modulation on Unsteady MHD Free Convection Flow Through Porous Medium in Slip-Flow Regime with Entropy

Walailak Journal of Science and Technology, 2013
The effect of radiation and periodic oscillation of the gravitational field on free-convection from a vertical plate is investigated. It is assumed that the gravity modulation is given by a harmonic function superimposed on a constant.
Satish Chandra RAJVANSHI, Baljinder Singh SAINI, Bhawn JEET   +2 more
doaj   +1 more source

MODULATION TRANSFER FUNCTIONS OF THE IONIZATION CHAMBER [PDF]

American Journal of Roentgenology, 1969
The blur in the measurement system is analyzed by bringing into the dosimetric system the concept of Modulation Transfer Function (MTF) which has recently been introduced into the radiographic system with fruitful results in the analysis of images.In this paper, the dosimetry, in air and in depth, of 190 kvp.
openaire   +2 more sources

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Modulation Transfer Function Extraction and Parametric Effects

Havacılık ve Uzay Teknolojileri Dergisi
We compute the optical transfer function and corresponding satellite image estimate in order to test validity of our modulation transfer function (MTF) extraction algorithms. The test targets allow MTF computation by using slanted edge and sine wave star
Kamil B. Alıcı
doaj  

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Research on modulation transfer function of the linear-array CCD for hyperspectral imager

MATEC Web of Conferences, 2017
As an image-spectrum merging technology, hyperspectral imaging has been used in battlefield reconnaissance rapidly．Based on response of CCD to the sine input signal, the period and extremal positions of output signal were analyzed and simulated ...
Hong qiang Zhang, Chun hong Wang
doaj   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Analytical Investigation of Frequency Behavior in Tunnel Injection Quantum Dot VCSEL [PDF]

Journal of Optoelectronical Nanostructures, 2018
The frequency behavior of the tunnel injection quantum dot vertical cavitysurface emitting laser (TIQD-VCSEL) is investigated by using an analyticalnumericalmethod on the modulation transfer function.
Mehdi Riahinasab, Elham Darabi
doaj