Results 71 to 80 of about 776,397 (353)
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Electrical 2{\pi} phase control of infrared light in a 350nm footprint using graphene plasmons
Modulating the amplitude and phase of light is at the heart of many applications such as wavefront shaping, transformation optics, phased arrays, modulators and sensors.
Gao, Yuanda +10 more
core +1 more source
The calcium-sensing receptor as a regulator of cellular fate in normal and pathological conditions [PDF]
The calcium-sensing receptor (CaSR) belongs to the evolutionarily conserved family of plasma membrane G protein-coupled receptors (GPCRs). Early studies identified an essential role for the CaSR in systemic calcium homeostasis through its ability to ...
Benoit, Yves +3 more
core +1 more source
Let \tau be a radical for the category of left R -modules for a ring R . If
Büyükaşık, Engin +2 more
openaire +5 more sources
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Frequency Bin Entangled Photons
A monochromatic laser pumping a parametric down conversion crystal generates frequency entangled photon pairs. We study this experimentally by addressing such frequency entangled photons at telecommunication wavelengths (around 1550 nm) with fiber optics
A. T. Nguyen +7 more
core +3 more sources
Combinations of isoform-targeted histone deacetylase inhibitors and bryostatin analogues display remarkable potency to activate latent HIV without global T-cell activation [PDF]
Current antiretroviral therapy (ART) for HIV/AIDS slows disease progression by reducing viral loads and increasing CD4 counts. Yet ART is not curative due to the persistence of CD4+ T-cell proviral reservoirs that chronically resupply active virus ...
Albert, Brice J +8 more
core +2 more sources
Modules with Simple Multiplicity Modules
Let \(G\) be a finite group, \(\mathcal O\) be a complete local commutative noetherian ring with an algebraically closed residue field \(k\) of nonzero characteristic \(p\). Let \(M\) be an indecomposable \({\mathcal O}G\)-module with vertex \(P\), \(\delta\) be a local point of \(P\) on \(\text{End}_{\mathcal O}(M)\) and \(V\) be the multiplicity \(k_*
openaire +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Modulation of Autophagy for Controlling Immunity
Autophagy is an essential process that maintains physiological homeostasis by promoting the transfer of cytoplasmic constituents to autophagolysosomes for degradation. In immune cells, the autophagy pathway plays an additional role in facilitating proper
Young Jin Jang +2 more
doaj +1 more source

