Results 81 to 90 of about 776,397 (353)
Nano Select, 2023 We present an electro‐optic modulator exploiting a metamaterial made of an array of vanadium dioxide nanorods operating in epsilon‐near‐zero regime as the active switching material in a silicon waveguide. The modulator takes advantage of the insulator‐to‐
Gregory Tanyi +2 more
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CFTR Modulator Therapies: Potential Impact on Airway Infections in Cystic Fibrosis
Cells, 2022 Cystic Fibrosis (CF) is an autosomal recessive disease caused by mutations in the gene encoding for the Cystic Fibrosis Transmembrane conductance Regulator (CFTR) protein, expressed on the apical surface of epithelial cells.
Francesca Saluzzo +6 more
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Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
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Optical Transmitters without Driver Amplifiers—Optimal Operation Conditions
Applied Sciences, 2018 An important challenge in optical communications is the generation of highest-quality waveforms with a Mach–Zehnder modulator with a limited electrical swing (Vpp).
Arne Josten +4 more
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Modulacja i modulatory relacji politycznych – ujęcie teoriopolityczne
Politeja, 2022 MODULATION AND MODULATORS OF POLITICAL RELATIONS: POLITICAL THEORY APPROACH The article aims to explain the phenomenon of modulation of political relations and to present the proposition of theoretical systematization of modulators of political ...
Piotr Obacz
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FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
On the modulation of TRPM channels: Current perspectives and anticancer therapeutic implications
Frontiers in Oncology, 2023 The transient melastatin receptor potential (TRPM) ion channel subfamily functions as cellular sensors and transducers of critical biological signal pathways by regulating ion homeostasis. Some members of TRPM have been cloned from cancerous tissues, and
Tania Ciaglia +4 more
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Glasgow Mathematical Journal, 2006 Let R be a ring. An R-module M is called a (weak) duo module provided every (direct summand) submodule of M is fully invariant. It is proved that if R is a commutative domain with field of fractions K then a torsion-free uniform R-module is a duo module if and only if every element k in K such that kM is contained in M belongs to R.
Ozcan, A.C., Harmanci, A., Smith, P.F.
openaire +2 more sources
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Probing Mechanisms and Therapeutic Potential of γ-Secretase in Alzheimer’s Disease
Molecules, 2021 The membrane-embedded γ-secretase complex carries out hydrolysis within the lipid bilayer in proteolyzing nearly 150 different membrane protein substrates.
Michael S. Wolfe
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