Results 101 to 110 of about 776,397 (353)
50GHz Ge waveguide electro-absorption modulator integrated in a 220nm SOI photonics platform [PDF]
, 2015 We report waveguide-integrated Ge electro-absorption modulators operating at 1615nm wavelength with 3dB bandwidth beyond 50GHz and a capacitance of 10fF, A 2V voltage swing enables 4.6dB DC extinction ratio for 4.1dB insertion ...
Absil, P +10 more
core +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Proceedings of the American Mathematical Society, 1984 The Alexander modules of a link are the homology groups of the universal abelian cover of the complement of the link. For a link of n n -spheres in S n + 2 {S^{n + 2}} , we show that, if n ⩾ 2 n \geqslant 2
openaire +2 more sources
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Positive allosteric modulators of the a-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor [PDF]
, 2010 L-glutamate is the major excitatory neurotransmitter in the mammalian central nervous system (CNS) and plays a fundamental role in the control of motor function, cognition and mood.
Grove, Simon J .A. +4 more
core +1 more source
Notices of the American Mathematical Society, 2023 This is an overview of the idea of a crossed module. For a group, the triple that consists of the group, its group of automorphisms, and the canonical homomorphism from the group to its group of automorphisms constitutes a crossed module. Crossed modules arise from the identities among the relations of the presentation of a group, from the extension ...
openaire +3 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Analysis of magnetically-controlled processes in pulse-modulation systems [PDF]
, 1969 Investigation established analytic expressions for the design of pulse modulators with modulating signal control of the reset level of flux in a nonlinear magnetic core.
Veillette, L. J.
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Revista de Ciências AgroveterináriasThis study aimed to evaluate food additives for the replacement of monensin and virginiamycin in high-grain diets for cattle. A Latin square experimental design was adopted, represented by four treatments (functional oil, yeast, tannin and control ...
Saulo Alberto do Carmo Araújo +4 more
doaj +1 more source