Results 161 to 170 of about 1,019,672 (318)
Command Module Flammability Considerations 2.5.68 [PDF]
Command Module Flammability Considerations document written by George Low, PA/Manager of the Apollo Spacecraft ...
Low, George
core
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
A Rapid and Inexpensive Method for Finding the Basic Parameters of Involute Helical Gears
The paper proposes a rapid, straightforward, and inexpensive method for finding the basic parameters of helical gears with an involute profile. The basic parameters envisaged are the normal module, normal profile shift coefficient, and the helix angle ...
Stelian Alaci +5 more
doaj +1 more source
Astrocyte heterogeneity in brain metastases
Astrocytes emerge as pivotal regulators of metastatic colonization, survival, immune remodeling, and therapy response associated with an increasing heterogeneity that requires spatially and longitudinally resolved approaches to uncover regulatory programs and guide context‐specific therapies.
Carolina Hernández‐Oliver +2 more
wiley +1 more source
CG6 Information Management. S [PDF]
(This information is for guidance purposes only. It may vary due to changes in the format of the guide, errors, omissions or any incidents occurred during the semester in which the module takes place.
Core Module
core
Translating whole‐genome doubling into precision medicine in cancer
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
CEACAM1 participation in breast cancer progression
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Simulation of the effects of global irradiance, ambient temperature and partial shading on the output of the photovoltaic module using MATLAB/Simulink and ICAP/4 [PDF]
This thesis is investigates the effects of operating conditions on the output of a photovoltaic module and describes methods used for maximising the power output of the module.
Polyanskaya, Evgeniya
core +1 more source
Spatial biology in cancer epigenetics
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source

