Results 161 to 170 of about 1,272,107 (311)

From Concept to Classroom: Developing and Evaluating Pain Smart, a School-Based Pain Education Module. [PDF]

Can J Pain
Bogard I, Kamper SJ, Sortwell A, Montgomery LRC, Williams CM, Costello J, Yamato TP.   +6 more
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

A cascaded U-nets model based on hybrid attention for video anomaly detection. [PDF]

PLoS One
Li S, Jiang N, Qin J, Gong J, Pang Y, Wang F.   +5 more
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Land Use Intensity Module: Land Use in Rural New Zealand Version 1 [PDF]

This document outlines the development of the dynamic functions and simple algorithms that make up the Land Use in Rural New Zealand (LURNZ) land-use intensity module.
Joanna Hendy, Suzi Kerr
core  

Digitally Assisted Training System for Home-Based Scoliosis Therapy: Proof-of-Concept and Technical Verification Study. [PDF]

JMIR Rehabil Assist Technol
Günther F, Hunger S, Werner M, Landerer N, Heyde CE, Drossel WG.   +5 more
europepmc   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Mechanisms of INO80 remodeling. [PDF]

Biochem Soc Trans
Shukla S, Bartholomew B.
europepmc   +1 more source

Regular modules and $V$-modules

Hiroshima Mathematical Journal, 1981
openaire   +3 more sources

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source