Results 1 to 10 of about 394,439 (267)

Conceptualising the experience of having TB: a global qualitative study [PDF]

IJTLD Open
BACKGROUND: TB and aspects of its treatment are known to impair health-related quality of life, but data are lacking on how pulmonary TB is experienced from the standpoint of affected individuals.
D. Oberdhan, M. Hill, A. Gillman, N. McGale, J. Dandy, T. Abdullaev, M. Dara   +6 more
doaj   +2 more sources

A Patient-Relevant Measurement Strategy to Assess Clinical Benefit of Novel Therapies for Non-metastatic Cutaneous Squamous Cell Carcinoma [PDF]

Oncology and Therapy
Introduction Although cutaneous squamous cell carcinoma (CSCC) is the second most common type of skin cancer, research describing the patient experience is limited.
Diana Rofail, Anna Ciesluk, Teya Lovell, Patrick Marquis, Matthew G. Fury, Chieh-I Chen   +5 more
doaj   +2 more sources

Assessing tolerability with the Functional Assessment of Cancer Therapy item GP5: psychometric evidence from LIBRETTO-531, a phase 3 trial of selpercatinib in medullary thyroid cancer [PDF]

Journal of Patient-Reported Outcomes
Background This psychometric analysis generated evidence to support the use of the Functional Assessment of Cancer Therapy item GP5 (GP5) as a measure of tolerability and confirms the appropriateness of categorizing “high side-effect burden” using a ...
Antoine Regnault, Laurine Bunod, Angely Loubert, Marcia S. Brose, Lisa M. Hess, Patricia Maeda, Yan Lin, Rebecca M. Speck, Adrienne M. Gilligan, Nalin Payakachat   +9 more
doaj   +2 more sources

Time Without Transfusion Reliance (TWiTR): Integrating Survival Quality Into Myelofibrosis Treatment Strategies Based on the Phase 3 SIMPLIFY‐1, SIMPLIFY‐2, and MOMENTUM Trials [PDF]

eJHaem
Introduction Myelofibrosis is characterized by debilitating constitutional symptoms and anemia, which negatively impact survival and quality of life.
Ruben A. Mesa, Moshe Talpaz, Flora Mazerolle, Boris Gorsh, Manal M'Hari, Antoine Regnault, Catherine Ellis, Zhaohui Wang, Molly Purser, Tom Liu, Bryan Strouse, Dwaipayan Patnaik   +11 more
doaj   +2 more sources

Profitability of Photovoltaic and Energy Storage System in a Foundry Plant [PDF]

Archives of Foundry Engineering, 2023
The article presents a case study on the effectiveness of photovoltaic farm and battery energy storage in one of the Polish foundries. In the study, we consider two investment options: stand-alone PV farm of 1MWp and the farm together with battery energy
A. Stawowy, R. Wrona, M. Sawczuk, D. Lasek   +3 more
doaj   +1 more source

Establishing clinically meaningful within-individual improvement thresholds for eight patient-reported outcome measures in people with relapsing-remitting multiple sclerosis

Journal of Patient-Reported Outcomes, 2023
Background As disease-modifying therapies do not reverse the course of multiple sclerosis (MS), assessment of therapeutic success involves documenting patient-reported outcomes (PROs) concerning health-related quality of life, disease and treatment ...
Nupur Greene, Stéphane Quéré, Denise P. Bury, Flora Mazerolle, Manal M’Hari, Angély Loubert, Antoine Regnault, Keiko Higuchi   +7 more
doaj   +1 more source

Development of the Myasthenia Gravis (MG) Symptoms PRO: a case study of a patient-centred outcome measure in rare disease

Orphanet Journal of Rare Diseases, 2021
Background Myasthenia gravis (MG) is a chronic autoimmune neuromuscular disease, characterised by fluctuating muscle weakness which makes it challenging to assess symptom severity.
Sophie Cleanthous, Ann-Christin Mork, Antoine Regnault, Stefan Cano, Henry J. Kaminski, Thomas Morel   +5 more
doaj   +1 more source

A Mixed-Methods Study to Better Measure Patient-Reported Pain and Fatigue in Soft Tissue Sarcoma

Oncology and Therapy, 2023
Introduction Pain and fatigue are commonly reported by patients with soft tissue sarcoma (STS) as distressing symptoms, yet no patient-reported outcome (PRO) measures have been validated or developed specifically for STS.
Louise Barrett, Emma Elliott, Maarten Voorhaar, Anders Ingelgård, Ingolf Griebsch, Brendon Wong, Jessica Mills, Phoebe Heinrich, Stefan Cano   +8 more
doaj   +1 more source

Development and psychometric evaluation of the assessment of self-injection questionnaire: an adaptation of the self-injection assessment questionnaire

Health and Quality of Life Outcomes, 2020
Background Patient-reported outcome (PRO) instruments provide robust and effective means of evaluating patients’ treatment experience; however, none adequately cover experience using self-injection devices with enhanced features, such as an ...
Farrah Pompilus, Anna Ciesluk, Sara Strzok, Valerie Ciaravino, Kristina Harris, Boglarka Szegvari, Irina Mountian, Sophie Cleanthous, Juliette Meunier   +8 more
doaj   +1 more source

Development and content validation of the Symptoms Evolution of COVID-19: a patient-reported electronic daily diary in clinical and real-world studies

Journal of Patient-Reported Outcomes, 2022
Background At the onset of the COVID-19 pandemic, there was limited understanding of symptom experience and disease progression. We developed and validated a fit-for-purpose disease-specific instrument to assess symptoms in patients with COVID-19 to ...
Diana Rofail, Nadine McGale, Joseph Im, Alissa Rams, Krystian Przydzial, Vera Mastey, Sumathi Sivapalasingam, Anna J. Podolanczuk   +7 more
doaj   +1 more source