Results 111 to 120 of about 365,643 (284)

Nanoscale Covalent Organic Framework Confinement Enables Ultratough and Hyperelastic Hydrogels Applied as High‐Performance Electrolytes

Advanced Science, EarlyView.
Confinement by nanoscale covalent organic frameworks reinforces hydrogels, imparting exceptional mechanical strength and ionic conductivity for high‐performance electrolyte applications. ABSTRACT Hydrogels are widely applied in various fields, including energy storage and flexible electronics. However, their mechanical properties often fail to meet the
Peiyao Yan, Wei Zhao, Hao Wang, Lu Wu, Yedong Ma, Binting Huang, Hantao Xu, Xueyan Liu, Siqi Liu, Xinyu Dong, Xiaoyang Zhang, Wei Zhai, Weiwei Zhang, Lin Xu, Dan Zhao, Chaobin He   +15 more
wiley   +1 more source

Transdermal Delivery of an mRNA‐Liposome Vaccine via Dissolving Microneedle to Preserve Vaccine Activity and Enhance Immune Activation

Advanced Science, EarlyView.
An mRNA‐liposome vaccine via dissolving microneedles (ML‐DMN) enables efficient skin‐targeted delivery while preserving mRNA integrity and allowing sustained antigen expression. Unlike intramuscular (IM) injection, ML‐DMN engages skin‐resident immune cells, activates antigen‐presenting cells (APCs), and induces strong T cell and cytokine responses at ...
Jeehye Nam, JiWon Ahn, Jiwoo Shin, Nahong Lee, Youjin Lee, Sung min Cho, Paul Kim, Geonwoo Kang, Sang‐Jun Ha, Hyungil Jung   +9 more
wiley   +1 more source

A Polinton-like Virus of C. parva Inhibits the Population Growth of a Newly Isolated Relative of Tethysvirus ontarioense

Viruses
The previous discovery of genomes of Polinton-like viruses (PLVs) associated with viruses of Chrysochromulina parva stimulated this research to determine the biological nature of these putative viral hyperparasites. Purification of C.
George R. Thomas, Ichiro Inamoto, Christine N. Palermo, Gurshan Bajaj, Steven M. Short   +4 more
doaj   +1 more source

Divergent Roles of mGlu2 and mGlu3 Receptors in Amyloid‐β Production and Cognitive Dysfunctions in Alzheimer's Disease

Advanced Science, EarlyView.
This study explores the opposing effects of the mGluR2 and mGluR3 receptors on amyloid precursor protein processing. mGluR2 promotes amyloidogenic cleavage, while mGluR3 favors non‐amyloidogenic pathways. Using a brain‐penetrant nanobody as a mGluR2 positive allosteric modulator, the study uncovers how its chronic activation aggravates amyloid‐β burden
Pierre‐André Lafon, Mireille Elodie Tsitokana, Ugo Guy Alenda, Yen‐Ling Lian, Clémentine Eva Philibert, Mathieu Oosterlaken, Marta Cimadevila, Gaëlle Dudon, Jessica Monnic, Salomé Roux, Julie Bessié, Séverine Diem, Franck Vandermoere, Laurent Prézeau, Patrick Chames, Julie Kniazeff, Sylvie Claeysen, Anaïs Menny, Jean‐Philippe Pin, Véronique Perrier, Jianfeng Liu, Philippe Rondard   +21 more
wiley   +1 more source

Hamlet in Slovenia: From Myth to Theatre [PDF]

, 2012
Zlatnar Moe Marija
core   +2 more sources

What’s the difference? Jobseeker perspectives on employment assistance [PDF]

This qualitative study from the Brotherhood of St Laurence illustrates the challenges faced by jobseekers navigating today’s labour market. Drawing on insights from service users in four focus groups with 39 clients from the Carlton, Moe and ...
Eve Bodsworth
core  

CRISPR/Cas13a: Compensatory Target Activation Mechanism

Advanced Science, EarlyView.
CRISPR/Cas13a‐CTAM as a novel compensatory target activation mechanism that enables synergistic activation of Cas13a via two independently editable short RNA effectors. This dual‐effector system maintains enzymatic activity comparable to traditional single‐effector while significantly enhancing flexibility, sensitivity, and application scope.
Bowen Jiang, Tenghua Zhang, Yao Lu, Shujun Zhou, Wenjing Xiao, Shuming Pan, Nan Shi, Yan Sheng, Jiaming Hu   +8 more
wiley   +1 more source

A prototype interface unit for microprocessor based Loran-C receiver [PDF]

An inexpensive data/command entry and CRT display system capable of alphanumeric and graphics moe operation and designed to operate in place of a separate ASCII terminal, is documented.
Novacki, S. M., III
core   +1 more source

Physical Implementation of Optical Material‐Based Neural Networks Processing Enabled by Long‐Persistent Luminescence

Advanced Science, EarlyView.
This study reports on the physical implementation of optical material‐based neural processing using long‐persistent luminescence as memory‐retention and nonlinear optical material. The system performs optical‐domain preprocessing with opto‐electronic interfaces for stimulus delivery and readout, enabling real‐time demonstrations including Pong gameplay
Sangwon Wi, Yunsang Lee
wiley   +1 more source

Integrating Machine Learning With Constant‐Potential Simulation to Unravel Charge‐Transfer Mechanisms in Electrochemical Nitrogen Fixation

Advanced Science, EarlyView.
Integrating interpretable machine learning with the fixed‐potential method reveals a novel mechanism: the catalytic activity of the electrochemical nitrogen reduction reaction is governed by partial charge transfer, induced by variations in the intermediate potential of zero charge under constant potential.
Yufei Xue, Dushuo Feng, Yuefei Zhang, Yang Zhang, Yalong Jiao, Aijun Du, Guoping Gao   +6 more
wiley   +1 more source