Results 91 to 100 of about 365,643 (284)
Six reasons why thermospheric measurements and models disagree [PDF]
The differences between thermospheric measurements and models are discussed. Sometimes the model is in error and at other times the measurements are, but it also is possible for both to be correct, yet have the comparison result in an apparent ...
Moe, Kenneth
core +1 more source
G3BP1 Succinylation at K413 is Critical for Cardiac Function by Modulating PI3K‐AKT‐mTOR Signal Axis
Schematic illustrating the impact of G3BP1 succinylation at K413 on cardiac function. In the healthy human heart, G3BP1 succinylation maintains homeostatic mTOR signaling. In patients with dilated cardiomyopathy (DCM) and heart failure (HF), G3BP1 de‐succinylation induces RagA expression and disrupts the binding of the TSC1/2 complex, leading to the ...
Yuan Zhang +9 more
wiley +1 more source
Revolution fatigue – The lost promises of the Kyrgyz revolutions Kyrgyzstan has seen three rulers ousted through popular revolutions in its short thirty-years of independence, while the regimes became less democratic and the revolutions became more violent.
Born, Willemijn, Weerdesteijn, Maartje
openaire +2 more sources
PSMA8‐Containing 20S Proteasome Regulates Spermiogenesis and Male Fertility
PSMA8 assembles s20S proteasome that degrades specific substrates in elongating spermatids. Degradation of s20S‐substrates activates translation of FXR1‐target mRNAs, which are essential for mitochondrial sheath formation and sperm morphogenesis.
Huiwen Cao +7 more
wiley +1 more source
Failure Behavior in Mechanical Testing of Two Plywood Products Distributed in Korea
The structural performance was tested for two plywood products distributed in South Korea: Plywood for roof (RP) and plywood for concrete form (CP), in accordance with ASTM standards.
In-Hwan Lee +4 more
doaj
Training course for radiation safety technicians [PDF]
Course of instruction includes sections on basic information, natural radioactivity, properties of alpha, beta, gamma, X rays, and neutrons, concepts of radiation units and dose determinations, shielding, biological effects, background radiation ...
Lasuk, S. R., Moe, H. J.
core +1 more source
In this study, the orange‐muscle giant abalone (Haliotis gigantea) is used as a model to identify a non‐coding SNP that disrupts the interaction between ITGA8 pre‐mRNA and the splicing factor ILF2, leading to altered ITGA8 splicing. These splicing changes promote carotenoid accumulation in abalone muscle through the regulation of tissue remodeling ...
Xiaohui Wei +17 more
wiley +1 more source
Restoring Iron Homeostasis via Smoothened Inhibition: A Novel Strategy Against Hearing Loss
. ABSTRACT Sensorineural hearing loss (SNHL) induced by noise or aminoglycoside antibiotics is a significant public health concern without any FDA‐approved pharmaceutical therapies. Dysregulation of iron homeostasis and its subsequently induced ferroptosis has increasingly been identified as a key mechanism underlying cochlear hair cell (HC) damage ...
Huanyu Mao +9 more
wiley +1 more source
SpatialESD: Spatial Ensemble Domain Detection in Spatial Transcriptomics
ABSTRACT Spatial transcriptomics (ST) measures gene expression while preserving spatial context within tissues. One of the key tasks in ST analysis is spatial domain detection, which remains challenging due to the complex structure of ST data and the varying performance of individual clustering methods. To address this, we propose SpatialESD, a Spatial
Hongyan Cao +11 more
wiley +1 more source
Background Magnolia officinalis is a medicinal herb known for its pharmacological properties and as a potential natural feed additive. We aimed to assess the effects of dietary Magnolia officinalis extract (MOE) on the growth performance and immune ...
Chen Zhang +7 more
doaj +1 more source

