Results 41 to 50 of about 82,911 (254)

Effective exon skipping and dystrophin restoration by 2'-o-methoxyethyl antisense oligonucleotide in dystrophin-deficient mice. [PDF]

PLoS ONE, 2013
Antisense oligonucleotide (AO)-mediated exon-skipping therapy is one of the most promising therapeutic strategies for Duchenne Muscular Dystrophy (DMD) and several AO chemistries have been rigorously investigated. In this report, we focused on the effect
Lu Yang, Hongjing Niu, Xianjun Gao, Qingsong Wang, Gang Han, Limin Cao, Chunquan Cai, Jan Weiler, Haifang Yin   +8 more
doaj   +1 more source

Uni-Perceiver-MoE: Learning Sparse Generalist Models with Conditional MoEs

Advances in Neural Information Processing Systems 35, 2022
To build an artificial neural network like the biological intelligence system, recent works have unified numerous tasks into a generalist model, which can process various tasks with shared parameters and do not have any task-specific modules. While generalist models achieve promising results on various benchmarks, they have performance degradation on ...
Jinguo Zhu, Xizhou Zhu, Wenhai Wang, Xiaohua Wang 0001, Hongsheng Li 0001, Xiaogang Wang 0001, Jifeng Dai   +6 more
openaire   +3 more sources

Snap‐Through–Driven Liquid Crystal Elastomers for High‐Power Remote Microneedle Actuation Toward Smart Livestock Systems

Advanced Functional Materials, EarlyView.
A magnetically assisted snap‐through liquid crystal elastomer transforms photochemical deformation into a high‐power mechanical impulse, enabling remote microneedle actuation and highlighting its potential for future smart livestock intervention systems.
Chae Won Lee, Nankyung Kim, SeungHyun Park, Dae Seok Kim   +3 more
wiley   +1 more source

Disentangling Bulk and Surface Contributions to Charge and Discharge Fading in High‐Voltage LiCoO2

Advanced Functional Materials, EarlyView.
High‐voltage operation of LiCoO2 accelerates capacity fading through bulk and surface degradation. By introducing a LiTaO3 coating to selectively suppress surface degradation, bulk and surface contributions to charge and discharge fading are decoupled.
Hyungjoon Moon, Sangbin Park, Jaewoo Jung, Seongeun Lee, Chanwoo Jung, Min‐Sik Park, Won‐Sub Yoon   +6 more
wiley   +1 more source

Fullerene‐Mediated Iodine Immobilization at Buried Interfaces in Sn–Pb Perovskite Solar Cells

Advanced Functional Materials, EarlyView.
Indene‐C60 bisadduct (ICBA) accumulates at the buried interface of inverted tin‐lead perovskite solar cells, limiting undesired electron extraction while maintaining efficient hole transport. ICBA simultaneously scavenges molecular iodine, mitigating Sn2+ oxidation and interfacial recombination. This coupled electronic‐chemical regulation delivers 22.7%
Chi‐Jing Huang, Yi‐Sheng Lin, Matyas Daboczi, Yueyao Dong, Anuj Kumar Singh, Luis Lanzetta, Yun‐Shan Li, Chang‐Hao Wang, Huan‐Wei Lin, Wei‐Jia Qiu, Yi‐Ting He, Chun‐Fu Chang, Sanjayan Sathasivam, Derya Baran, Thomas J. Macdonald, Chieh‐Ting Lin   +15 more
wiley   +1 more source

Evaluation of Physical and Mechanical Properties of Fiber-Reinforced Poplar Scrimber

BioResources, 2016
The mechanical properties of poplar scrimber reinforced with glass fiber mesh were investigated. The influence of the different structures and densities were studied with respect to the modulus of rupture (MOR), modulus of elasticity (MOE), and impact ...
Xiaolei Guo, Yubin Lin, Bin Na, Xingyu Liang, Mats Ekevad, Futang Ji, Lingling Huang   +6 more
doaj   +1 more source

Genetic Improvement of Sawn-Board Stiffness and Strength in Scots Pine (Pinus sylvestris L.)

Sensors, 2020
Given an overall aim of improving Scots pine structural wood quality by selective tree breeding, we investigated the potential of non-destructive acoustic sensing tools to accurately predict wood stiffness (modulus of elasticity, MOE) and strength ...
Irena Fundova, Henrik R. Hallingbäck, Gunnar Jansson, Harry X. Wu   +3 more
doaj   +1 more source

A Fully Defined GelMA‐Based Matrix Allows Fine Tuning of Tissue‐Relevant Biomechanical and Biochemical Cues for Organoid Culture

Advanced Healthcare Materials, EarlyView.
A fully defined GelMA‐based ECM platform integrates tunable tissue‐relevant stiffness with laminin–entactin biochemical supplementation to support mouse small intestinal organoid growth. Coordinated control of mechanical and biochemical cues promotes robust proliferation, budding morphogenesis, differentiation, and passaging, providing a reproducible ...
Junyi Liu, Su Su Htwe, Lay Poh Tan, Yen Choo   +3 more
wiley   +1 more source

Investigation on Modulus of Elasticity of Badminton String by Response Surface Methodology

Advances in Materials Science and Engineering, 2022
Modulus of elasticity (MOE) is one of the important indexes to evaluate the performance of badminton string. In this work, a series of tensile testing were performed to explore the changes in MOE at different temperature, humidity, and tensile rate ...
Feng Ji
doaj   +1 more source

Nanomaterial Strategies for Pulmonary Delivery of Immunotherapeutics in Lung Cancer Treatment

Advanced Healthcare Materials, EarlyView.
Inhalable immunotherapeutic nanomedicines enable organ‐selective immune modulation by overcoming pulmonary delivery barriers and concentrating therapy within lung tumors. This Review defines how nanomaterial properties govern airway deposition, retention, cellular partitioning, and immune activation across vaccines, checkpoint blockade, STING agonists,
Han Zhang, Wei Tang
wiley   +1 more source