Results 141 to 150 of about 17,063 (321)

Polo‐like kinases and UV‐induced skin carcinogenesis: What we know and what's next

Photochemistry and Photobiology, EarlyView.
The polo‐like kinase (PLK) family plays distinct and critical roles in the regulation of cell cycle progression, and its dysregulation has been implicated in various cancers. Ultraviolet (UV) radiation is a well‐established environmental factor in the development of skin cancer.
Tanya Jaiswal, Durdana Muntaqua, Gagan Chhabra, Nihal Ahmad   +3 more
wiley   +1 more source

PLK4 is a potential therapeutic target in nonmelanoma skin cancers: Evidence from molecular and in vivo studies

Photochemistry and Photobiology, EarlyView.
Exposure to solar ultraviolet radiation is the main etiologic driver of nonmelanoma skin cancers (NMSCs), including basal cell (BCC) and cutaneous squamous cell carcinomas (cSCC), which are the most prevalent types of cancers in the US. In this study, we demonstrate that the serine/threonine kinase Polo‐like kinase 4 (PLK4) is overexpressed in NMSCs ...
Mary A. Ndiaye, Debra R. Garvey, Gagan Chhabra, Chandra K. Singh, Minakshi Nihal, Nihal Ahmad   +5 more
wiley   +1 more source

Harnessing blue light photobiomodulation for cancer therapy: Evidence from a systematic review

Photochemistry and Photobiology, EarlyView.
Conventional treatments for various types of cancer are often associated with tumor recurrence and aggressiveness. Photobiomodulation with blue light (BL; 450–470 nm) emerges as a promising alternative with antitumor effects. This systematic review, with 37 in vitro and in vivo studies from 2002 to 2024, revealed that BL reduces cell viability ...
Bárbara Evelyn Santos de Lima, Rebeca Barros Nascimento, Ana Paula Mariano Santos Ginez, Maria Stella Moreira, Rebeca Boltes Cecatto, Rodrigo Labat Marcos, Maria Fernanda Setúbal Destro Rodrigues   +6 more
wiley   +1 more source

Active surveillance in older adults with basal cell carcinoma: A survey amongst European dermatologists

Journal of the European Academy of Dermatology and Venereology, EarlyView.
L. Van Coile, J. E. Mangnus, E. Backman, N. W. J. Kelleners‐Smeets, S. F. K. Lubeek, I. Hoorens   +5 more
wiley   +1 more source

Protocol: Strategies to Enhance Inclusion in Informed Consent Practice for People With Vision and/or Hearing Support Needs: A Systematic Review

Campbell Systematic Reviews, Volume 21, Issue 4, December 2025.
ABSTRACT An equitable and accessible informed consent process is needed to support agency and mutual decision‐making. This systematic review aims to gather and characterise the evidence supporting methods that enhance inclusion and accessibility in informed consent practice for people with vision and/or hearing support needs.
Fleur O'Hare, Sujani Thrimawithana, Aimee Clague, Eden G. Robertson, David Foran, Caroline Ondracek, Camille Paynter, Tessa Saunders, Lauren N. Ayton   +8 more
wiley   +1 more source

Painful, bleeding fingertip papule

JAAD Case Reports, 2022
Jane Gay, BA, Sarah Simpson, MD, Patrick Rush, DO, Alex Holliday, MD   +3 more
doaj   +1 more source

What Constitutes a Clear Margin in Mohs Surgery? [PDF]

Dermatol Surg, 2022
Phillips W, Shah K, Lee EH, Nehal K.
europepmc   +1 more source

Infiltrative Recurrent Eccrine Spiradenoma of the Anterior Neck Treated Using Mohs Micrographic Surgery [PDF]

, 2013
Rajib R. Rahim, Neil Rajan, J.A.A. Langtry   +2 more
openalex   +1 more source

Impact of Direct Oral Anticoagulant Uptake on Hospitalizations for Stroke/Transient Ischemic Attack, Intracranial Hemorrhage, and Gastrointestinal Bleeding in Individuals With Atrial Fibrillation: A Population‐Based Study

Fundamental &Clinical Pharmacology, Volume 39, Issue 6, December 2025.
ABSTRACT Background Direct‐acting oral anticoagulants (DOACs) have largely replaced warfarin for stroke prevention in patients with atrial fibrillation, yet their population‐level impact on health outcomes and costs remains unclear. We examined whether the widespread uptake of DOACs was associated with changes in hospitalization rates and costs for ...
Tony Antoniou, Daniel McCormack, Tianru Wang, Mina Tadrous, Tara Gomes   +4 more
wiley   +1 more source

ChatGPT underperforms in triaging appropriate use of Mohs surgery for cutaneous neoplasms. [PDF]

JAAD Int, 2023
O'Hern K, Yang E, Vidal NY.
europepmc   +1 more source