Results 41 to 50 of about 17,063 (321)

The role of harms and burdens in clinical practice guidelines: Lessons learned from the American Psychological Association's guideline development

Clinical Psychology: Science and Practice, EarlyView., 2020
Abstract Growing evidence supports the efficacy of various psychosocial interventions yet provides very little information about the potential harms and burdens of treatment. Lacking such information makes it difficult to make truly informed decisions about treatment options.
Raquel W. Halfond, Caroline Vaile Wright, Lynn F. Bufka   +2 more
wiley   +1 more source

10 Years of Mohs Micrographic Surgery in Denmark: Results from a Nationwide Cohort

Acta Dermato-Venereologica
Basal cell carcinoma is the most common skin malignancy and constitutes a burden for patients and society. Mohs micrographic surgery is a recommended treatment for high-risk basal cell carcinoma, but long-term outcomes of Mohs micrographic surgery in ...
Yuki M.F. Andersen, Katrine Karmisholt, Trine Høgsberg, Mia-Louise Nielsen, Amanda Brosbøl, Sascha Stave, Louise Schøsler, Silje Omland, Christine Aarenstrup Daugaard, Martin Glud   +9 more
doaj   +1 more source

Resource Planning for Neglected Tropical Disease (NTD) Control Programs: Feasibility Study of the Tool for Integrated Planning and Costing (TIPAC). [PDF]

, 2014
Resource Planning for Neglected Tropical Disease (NTD) Control Programs: Feasibility Study of the Tool for Integrated Planning and Costing (TIPAC)
A-F Gabrielli, Abdel N. Direny, Anne-Marie Desormeaux, AS Goldman, AS Goldman, Aya Yajima, B Liese, Bernard Kilembe, Brian K. Chu, C Hanson, DH Molyneux, Dharmpal P. Raman, Garib D. Thakur, Hannah Frawley, Jennifer Einberg, JH Kolaczinski, JO Gyapong, KA Grépin, Karleen Coly, Kathryn L. Zoerhoff, Kathryn R. Crowley, M Linehan, MA Brady, Margaret Baker, MC Baker, Mireille Jeudi, Molly A. Brady, Mustapha Sonnie, NB Kabatereine, Olivier J. Wouters, Philip W. Downs, PJ Hotez, PJ Lammie, Raj K. Pokharel, Roland Oscar, Santigie Sesay, Shekhar Sharma, Upendo Mwingira, Y Zhang   +38 more
core   +3 more sources

Shared decision making for perioperative antibiotic use during Mohs micrographic surgery on the lower extremitiesCapsule Summary

JAAD International
Background: While there is a higher risk of surgical site infection (SSI) on the lower extremities following Mohs micrographic surgery (MMS), antibiotic prophylaxis (AP) is debated.
Lisa Fronek, DO, Michael J. Davis, MD, Hubert T. Greenway, MD, Benjamin Kelley, MD   +3 more
doaj   +1 more source

Angiolymphoid hyperplasia with eosinophilia treated with Mohs micrographic surgery [PDF]

, 2019
A 60-year-old healthy man presented with several enlarging, tender, spontaneously bleeding, and episodically pruritic nodules on his ear. Five agminated pink-red papulonodules of the superior postauricular sulcus were noted on examination.
DeWitt, Corey M, Goldman, Glenn D, Norris, Ivy, Trivedi, Apoorva   +3 more
core  

Current Challenges in Hemostasis and Advances in Particle‐Assisted Styptic Devices

Advanced Healthcare Materials, EarlyView.
Here persistent limitations in hemostatic technologies are highlighted and cutting‐edge biomimetic, microparticle‐assisted, and nanoengineered systems with integrated drug delivery are showcased. Moreover, the article identifies fresh directions toward the next‐generation of multifunctional hemostatic devices with superior efficacy and accessibility ...
Daniele Baiocco, Zhibing Zhang, Neil M. Eisenstein, Nigel Tai, Liam M. Grover   +4 more
wiley   +1 more source

Advances and Strategies in Enhancing mRNA Cancer Vaccines

Advanced Materials, EarlyView.
Messenger RNA (mRNA) vaccines offer a powerful approach for cancer immunotherapy, but their clinical impact remains limited by delivery challenges and suboptimal immune activation. This review discusses key biological barriers and design strategies—including structural optimization, immunomodulation, organ targeting delivery, and advanced nanocarriers ...
Miao Zhang, Shengqi Chen, Haijun Hu, Yenhui Ong, Qianqian Ni   +4 more
wiley   +1 more source

Spatially Programmable Electroadhesive Enables In Situ Site‐Selective Functional Coupling

Advanced Materials, EarlyView.
A light‐activated, in situ spatially programmable bioadhesive (STICH) enables microscale, site‐selective integration of bioelectronic devices with wet tissue. It achieves robust mechanical bonding and low‐impedance electrical coupling, enabling reconfigurable neuromodulation and directional electromechanical sensing in vivo and ex vivo.
Yuting Guo, Zhuoming Liang, Guoshi Xu, Zhen Gu, Yuheng Xu, Michael Raphael Panganiban, Xue Cai, Jet Yong Kiat Lim, Jiguang Zhang, Jingxiu Huang, Tingting Fan, Qi Gu, Yuxin Liu   +12 more
wiley   +1 more source

PPP1R3B Suppresses Atherosclerosis by Promoting the M2 Polarization of Macrophages Through Glycogen Metabolic Reprogramming

Advanced Science, EarlyView.
PPP1R3B induces anti‐inflammatory M2 macrophage polarization and maintains energy supply in plaques. Its absence accelerates plaque progression. PPP1R3B regulates M2 macrophage polarization and energy metabolism via phosphorylated STAT3 (p‐STAT3), which plays a dual role by activating anti‐inflammatory transcriptional programs through the PPAR‐γ/PGC‐1α/
Lin Shen, Junchao Yu, Weiqian Chen, Yanran Bi, Zhangyu Yang, Chenying Lu, Chengli Jiang, Yang Yang, Minjiang Chen, Jianhua Zou, Lingchun Lv, Xiaoyuan Chen, Jiansong Ji   +12 more
wiley   +1 more source

Mohs Micrographic Surgery – what the gold standard in dermatologic surgery offers us. A Literature Review

Quality in Sport
Introduction and objective: Micrographic Mohs surgery, a highly precise surgical technique, has long been regarded as a cornerstone in dermatology for the treatment of various skin cancers.
Klaudia, Anna Kaźmierczak, Wiktoria Izdebska, Patrycja Sornek, Agata Borkowska, Anna Kiełb, Igor Pawlak, Anna Mich, Radosław Ciesielski, Jakub Stanek   +9 more
doaj   +1 more source