Results 41 to 50 of about 14,384,780 (329)

Adaptive molecular convergences

Communicative & Integrative Biology, 2010
Definitive identification of convergent evolution, the acquisition of the same biological trait in unrelated lineages, provides one of the most compelling sources of evidence for natural selection. Although numerous examples of convergent morphological evolution are well known (such as the independent development of wings in birds and mammals), cases ...
Todd A, Castoe, A P Jason, de Koning, David D, Pollock   +2 more
openaire   +2 more sources

Reações em cadeia: molar, molecular e (des)mobilização das máquinas de guerra

Revista Trágica, 2021
Deleuze e Guattari criam os conceitos de máquinas de guerra e revoluções moleculares buscando saídas para o impasse progressista no enfrentamento das formas de opressão contemporâneas.
Benito Eduardo Maeso, Vladimir Lacerda Santafé   +1 more
doaj   +1 more source

Structuring and extracting knowledge for the support of hypothesis generation in molecular biology

BMC Bioinformatics, 2009
BackgroundHypothesis generation in molecular and cellular biology is an empirical process in which knowledge derived from prior experiments is distilled into a comprehensible model. The requirement of automated support is exemplified by the difficulty of
Marco Roos, M. S. Marshall, Andrew P. Gibson, M. Schuemie, Edgar Meij, S. Katrenko, Willem Robert van Hage, Konstantinos Krommydas, P. Adriaans   +8 more
semanticscholar   +1 more source

Treponema pallidum PCR with blood and cerebrospinal fluid of newborns exposed and not exposed to syphilis during pregnancy

Journal of Infection in Developing Countries
Introduction: Congenital syphilis (CS) has severe adverse outcomes, including abortion and death. Diagnosis of CS in asymptomatic newborns remains difficult. This study aims to evaluate an in-house polymerase chain reaction (PCR) on cerebrospinal fluid (
Rafaela Caroline C Melo, Mauro C Ramos, Maria Lúcia R Rossetti, Vera Mileide T Grassi, Maurício O Colvero, Thales Augusto DT Marzarotto, Renan R Bonamigo   +6 more
doaj   +1 more source

Molecular Dynamics Simulations [PDF]

, 2003
A tutorial introduction to the technique of Molecular Dynamics (MD) is given, and some characteristic examples of applications are described. The purpose and scope of these simulations and the relation to other simulation methods is discussed, and the ...
Alder B J, Alder B J, Allen M P, Andersen H C, Barnes H A, Baschnagel J, Baschnagel J, Bennemann C, Binder K, Binder K, Binder K, Binder K, Binder K, Brandt A, Car R, Ceperley D M, Ceperley D M, Chowdhury D, Doi M, Evans D J, Fathollah Varnik, Frenkel D, Frenkel D, Green M S, Götze W, Hansen J-P, Herrmann H J, Hess S, Hess S, Hoover W G, Horbach J, Horbach J, Jürgen Horbach, Kadanoff L P, Kohn W, Kubo R, Kurt Binder, Landau D P, Landau L D, Mantegna R N, Marro J, Marx D, Metropolis N, Müller-Plathe F, Nielaba P, Paul W, Price D L, Rahman A, Rapaport D C, Reister E, Rouse P E, Sariban A, Scheidler P, Schöffel P, Sprik M, Todd B D, Tuckerman M E, Vollmayr K, Walter Kob, Wolfgang Paul   +59 more
core   +2 more sources

Molecular Diagnostics

Hematology, 2003
Abstract It is increasingly evident that molecular diagnostics, that is, the use of diagnostic testing to understand the molecular mechanisms of an individual patient’s disease, will be pivotal in the delivery of safe and effective therapy for many diseases in the future.
Rita M, Braziel, Margaret A, Shipp, Andrew L, Feldman, Virginia, Espina, Mary, Winters, Elaine S, Jaffe, Emanuel F, Petricoin, Lance A, Liotta   +7 more
openaire   +2 more sources

Pazopanib Combined With Vincristine and Irinotecan in Relapsed Wilms Tumor: Encouraging Outcomes in a Heavily Pretreated Pediatric Cohort

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background While Wilms tumor (WT) typically has a favorable prognosis, relapsed cases—especially those with high‐risk histology—remain therapeutically challenging after intensive frontline therapy. The combination of vincristine and irinotecan has demonstrated activity in pediatric solid tumors, and pazopanib, a multi‐targeted tyrosine kinase ...
Maria Debora De Pasquale, Alessandro Crocoli, Giuseppe Maria Milano, Pierluigi Di Paolo, Francesca Diomedi Camassei, Ida Russo, Annalisa Serra   +6 more
wiley   +1 more source

Molecular classification of breast cancer: An overview with emphasis on ethnic variations and future perspectives

Saudi Journal of Medicine and Medical Sciences, 2013
Morphologically identical breast cancers can display divergent clinical outcomes and responses to therapy. This can predominantly be attributed to molecular class differences that exist amongst histologically similar cancer types. Consequently, molecular
Mohamed A Shawarby, Dalal M Al-Tamimi, Ayesha Ahmed   +2 more
doaj   +1 more source

Mitochondrial molecular chaperones [PDF]

, 1994
After synthesis in the cytosol, most mitochondrial proteins must traverse mitochondrial membranes to reach their functional location. During this process, proteins become unfolded and then refold to attain their native conformation after crossing the ...
Atencio, Caplan, Caplan, Cheng, Craig, Cyr, Deshales, Eilers, Gambill, Glick, Glick, Hartl, Hartl, Hwang, Johnson, Kang, Kiebler, Langer, Liberek, Manning-Krieg, Neupert, Ostermann, Palleros, Rassow, Rospert, Sanders, Scherer, Schleyer, Schröder, Simon, Vestweber, Voos, Xia   +32 more
core   +1 more source

Survival for Children Diagnosed With Wilms Tumour (2012–2022) Registered in the UK and Ireland Improving Population Outcomes for Renal Tumours of Childhood (IMPORT) Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background The Improving Population Outcomes for Renal Tumours of childhood (IMPORT) is a prospective clinical observational study capturing detailed demographic and outcome data on children and young people diagnosed with renal tumours in the United Kingdom and the Republic of Ireland.
Naomi Ssenyonga, Angela Lopez‐Cortes, Reem Al‐Saadi, Suzanne Tugnait, Kristina Dzhuma, Catriona Duncan, Gordan Vujanic, Tanzina Chowdhury, Claudia Allemani, Michel P. Coleman, Kathy Pritchard‐Jones, the Children's Cancer and Leukaemia Group (CCLG) Renal Tumour Special Interest Group, Hugh Bishop, Anthony McCarthy, Pamela Kearns, Helen Rees, Amos Burke, Meriel Jenney, Jane Pears, Hamish Wallace, Milind Ronghe, Tanzina Chowdhury, Susan Picton, Emma Ross, Lisa Howell, Bernadette Brennan, Gail Halliday, Richard Grundy, Shaun Wilson, Sucheta Vaidya, Daniel Yeomanson, Jessica Bate, Vesna Pavasovic, Jessica Bate, Sabine Irtan, Jesper Brok, Minou Oostveen, Kristina Dzhuma, Mark Weeks, Richard Williams, Mark Powis, Max Pachl, Bruce Okoye, Naima Smeulders, Gordan Vujanic, Oystein Olsen, Tom Watson, Susan Shelmerdine, Dan Saunders, Angela Lopez-Cortes, Taryn Treger, Tom Jackson, Suzanne Tugnait, Lisa Howell, Tanzina Chowdhury, Sam Behjati, Angela Polanco   +56 more
wiley   +1 more source