Results 71 to 80 of about 15,058,672 (343)

NRASQ61R Expression in Lymphatic Endothelial Cells Causes Enlarged Vessels, Hemorrhagic Chylous Effusions, and High Mortality in a Mouse Model of Kaposiform Lymphangiomatosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Kaposiform lymphangiomatosis (KLA) is an aggressive complex lymphatic anomaly. Patients exhibit malformed lymphatic vessels and often develop hemorrhagic effusions and elevated angiopoietin‐2 (Ang‐2) levels. A somatic NRAS p.Q61R (NRASQ61R) mutation has been associated with KLA.
C. Griffin McDaniel, Patricia Pastura, Joshua P. Scallan, Timothy D. Le Cras   +3 more
wiley   +1 more source

Diagnostic Techniques for Soil-Transmitted Helminths – Recent Advances

Research and Reports in Tropical Medicine, 2021
Sumeeta Khurana,1 Shreya Singh,2 Abhishek Mewara1 1Department of Medical Parasitology, Post Graduate Institute of Medical Education and Research, Chandigarh, India; 2Department of Medical Microbiology, Post Graduate Institute of Medical Education and ...
Khurana S, Singh S, Mewara A
doaj  

Frequency Distribution of Keratinophilic Dermatophyte Fungi from the Soil of Different Zones in Isfahan Using Morphological and Molecular Methods

Advanced Biomedical Research, 2019
Background: Dermatophytes are one of the most important etiologic agents of cutaneous infections in humans and animals. The present study aimed to study the frequency distribution of keratinophilic dermatophyte fungi using conventional and molecular ...
Parvin Dehghan, Shabaz Yousefi Jalali, Mostafa Chadeganipour   +2 more
doaj   +1 more source

In vivo loss of tumorigenicity in a patient-derived orthotopic xenograft mouse model of ependymoma

Frontiers in Oncology, 2023
IntroductionEpendymomas (EPN) are the third most common malignant brain cancer in children. Treatment strategies for pediatric EPN have remained unchanged over recent decades, with 10-year survival rates stagnating at just 67% for children aged 0-14 ...
Jacqueline P. Whitehouse, Jacqueline P. Whitehouse, Hilary Hii, Chelsea Mayoh, Chelsea Mayoh, Marie Wong, Marie Wong, Pamela Ajuyah, Paulette Barahona, Louise Cui, Hetal Dholaria, Hetal Dholaria, Hetal Dholaria, Christine L. White, Christine L. White, Christine L. White, Molly K. Buntine, Molly K. Buntine, Jacob Byrne, Keteryne Rodrigues da Silva, Keteryne Rodrigues da Silva, Meegan Howlett, Meegan Howlett, Emily J. Girard, Emily J. Girard, Maria Tsoli, Maria Tsoli, David S. Ziegler, David S. Ziegler, David S. Ziegler, Jason M. Dyke, Jason M. Dyke, Sharon Lee, Paul G. Ekert, Paul G. Ekert, Paul G. Ekert, Paul G. Ekert, Paul G. Ekert, Mark J. Cowley, Mark J. Cowley, Nicholas G. Gottardo, Nicholas G. Gottardo, Nicholas G. Gottardo, Raelene Endersby, Raelene Endersby   +44 more
doaj   +1 more source

Pulmonary Dysfunction Is Associated With Sleep Study Abnormalities in Children With Sickle Cell Disease: A Multicenter Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Pulmonary dysfunction and sleep abnormalities are common in children with sickle cell disease (SCD) and are associated with worse clinical outcomes. Whether spirometry abnormalities are associated with polysomnography (PSG) findings remains unclear.
Ammar Saadoon Alishlash, Anis Rabbani Nourani, A. K. M. Fazlur Rahman, Dima Ezmigna, Tarig Ali‐Dinar   +4 more
wiley   +1 more source

Clinical implication of genetic composition and molecular mechanism on treatment strategies of HER2-positive breast cancers

Frontiers in Oncology, 2022
The current clinical management model of HER2-positive breast cancers is commonly based on guidelines, which in turn are based on the design and outcome of clinical trials.
Christopher Y.C. Chow, Christopher Y.C. Chow, Erich Ferdiansyah Lie, Cheng-Hsun Wu, Louis W.C. Chow, Louis W.C. Chow   +5 more
doaj   +1 more source

Physical Properties and Galactic Distribution of Molecular Clouds identified in the Galactic Ring Survey

, 2010
We derive the physical properties of 580 molecular clouds based on their 12CO and 13CO line emission detected in the University of Massachusetts-Stony Brook (UMSB) and Galactic Ring surveys.
Allen, Anderson, Bacmann, Benjamin, Benjamin, Bernard, Bloemen, Boulanger, Elmegreen, Falgarone, Federrath, Glover, Goldsmith, Gordon, Heitsch, Heyer, Heyer, Heyer, Jackson, James M. Jackson, Jill Rathborne, Julia Roman-Duval, Kerr, Klessen, Larson, Mandelbrot, Mark Heyer, Oort, Quireza, Rathborne, Rathborne, Reid, Robert Simon, Rohlfs, Roman-Duval, Scalo, Scalo, Simon, Sodroski, Strong, Tasker, Urquhart, Wakker, Whittet, Williams, Williams, Wolfire, Wolfire   +47 more
core   +1 more source

Molecular Bias

European Journal of Epidemiology, 2005
Bias is ubiquitous in research. The advent of the molecular era provides a unique opportunity to study the consequences of bias with large-scale empirical evidence accumulated in the massive data produced by the current discovery-oriented scientific effort, rather than just with theoretical speculations and constructs.
openaire   +3 more sources

The Fate (Outcome) of Clinically Apparent Single Lesion and Oligofocal Nephroblastomatosis Treated According to SIOP/GPOH Protocols for Wilms Tumor

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background The management of clinically apparent single lesions or oligofocal nephroblastomatosis, a facultative precursor of nephroblastoma, remains debated. Methods We retrospectively analyzed 37 patients with clinically apparent single or oligofocal nephroblastomatosis (two to three lesions per kidney) among 2347 patients registered between
Nils Welter, Jens‐Peter Schenk, Jenny Wegert, Manfred Gessler, Leo Kager, Stefan Wagenpfeil, Marina Müller, Jean‐Michel Wolff, Joerg Fuchs, Steven W. Warmann, Clemens‐Magnus Meier, Jochen Hubertus, Christian Rübe, Christian Vokuhl, Patrick Melchior, Lena Tschirner, Norbert Graf, Rhoikos Furtwängler   +17 more
wiley   +1 more source

Genus Datura: An Exploration of Genetic Alterations, Bioactive Compounds, and Pharmacological Activity

Plants
The genus Datura L. has pharmacological activities due to its source of bioactive compounds. The effects of bioactive compounds can vary depending on species, geographical location, and environmental conditions. The purpose of this review is to summarize
Khoirunnisa Assidqi, Nesti Fronika Sianipar, Dave Mangindaan, Chukwunwike Uchenna Enyi   +3 more
doaj   +1 more source