Results 81 to 90 of about 8,274,500 (305)
Molecular recognition features (MoRFs) in three domains of life [PDF]
, 2015 Intrinsically disordered proteins and protein regions offer numerous advantages in the context of protein–protein interactions when compared to the structured proteins and domains.
Uversky, Vladimir N. +3 more
core +1 more source
Adsorption of epoxy oligomer ED-20 and structure interfacial layer on the glass surface
Тонкие химические технологии, 2009 Adsorption of epoxy oligomer ED-20 on the glass surface have investigated. Comparison experimental and calculated on basis Landau-Lifshits theoretical model results indicated that adsorption in studied system was polymolecular.
A. N. Trofimov +5 more
doaj
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Information Theory Can Help Quantify the Potential of New Phenotypes to Originate as Exaptations
Frontiers in Ecology and Evolution, 2020 Exaptations are adaptive traits that do not originate de novo but from other adaptive traits. They include complex macroscopic traits, such as the middle ear bones of mammals, which originated from reptile jaw bones, but also molecular traits, such as ...
Andreas Wagner +2 more
doaj +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Emerging Infectious Diseases, 2010 Viruses are the major pathogens of community-acquired (CA) acute gastroenteritis (AGE) in children, but their role in healthcare-associated (HA) AGE is poorly understood.
Nigel A. Cunliffe +9 more
doaj +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Exploring the molecular basis of microphthalmia and anophthalmia: Insights from an Egyptian cohort
Purpose The aim of this study was to gain insight into the molecular spectrum of anophthalmia and microphthalmia (A/M) in the Egyptian population. Methods We studied a cohort of 34 patients from 31 unrelated families affected by the A/M spectrum.
Elmakkawy, Gehad +9 more
core +1 more source
Molecular Pathogenesis of Alzheimer’s Disease: Reductionist versus Expansionist Approaches
, 2009 Alzheimer’s disease (AD) is characterized clinically by dementia and pathologically by two hallmark lesions, senile plaques and neurofibrillary tangles.
George Perry +4 more
core +1 more source
Viruses, 2019 While bats are increasingly recognized as a source of coronavirus epidemics, the diversity and emergence potential of bat coronaviruses remains to be fully understood.
Susanna K.P. Lau +11 more
doaj +1 more source