Results 241 to 250 of about 7,530,679 (394)

Targeted metabolomics reveals novel diagnostic biomarkers for colorectal cancer

Molecular Oncology, EarlyView.
This study employed targeted metabolomic profiling to identify 302 distinct metabolites present in platelet‐rich plasma (PRP), revealing aberrant metabolic profiles amongst individuals diagnosed with colorectal cancer (CRC). Compared to carcinoembryonic antigen (CEA) and cancer antigen 19‐9 (CA199), our metabolite panel showed improved sensitivity ...
Zuojian Hu, Fenglin Shen, Yang Liu, Ziqing Zhong, Yongling Chen, Zhiyuan Xia, Cuiju Mo, Hongxiu Yu   +7 more
wiley   +1 more source

The 25th Anniversary of Current Issues in Molecular Biology: Marking This Significant Milestone. [PDF]

Curr Issues Mol Biol
Bhatia M.
europepmc   +1 more source

Lysosomal stress drives the release of pathogenic α-synuclein from macrophage lineage cells via the LRRK2-Rab10 pathway

iScience
Summary: α-Synuclein and LRRK2 are associated with both familial and sporadic Parkinson’s disease (PD), although the mechanistic link between these two proteins has remained elusive.
Tetsuro Abe, Tomoki Kuwahara, Shoichi Suenaga, Maria Sakurai, Sho Takatori, Takeshi Iwatsubo   +5 more
doaj  

Erratum: Shanghai Institute of Biochemistry: The molecular biology revolution [PDF]

, 1985
A. Anderson
openalex   +1 more source

KMT2A degradation is observed in decitabine‐responsive acute lymphoblastic leukemia cells

Molecular Oncology, EarlyView.
We demonstrate that decitabine (DEC) not only degrades the DNA methyltransferase DNMT1 but also the leukemic driver lysine methyltransferase KMT2A likely due to structural similarity of the DNA‐binding CXXC domains. DEC influences KMT2A downstream processes and synergizes with menin inhibitor revumenib (REV) to decrease leukemic cell proliferation, and
Luisa Brock, Lina Benzien, Sandra Lange, Maja Huehns, Alexandra Runge, Catrin Roolf, Anett Sekora, Gudrun Knuebel, Hugo Murua Escobar, Christian Junghanss, Anna Richter   +10 more
wiley   +1 more source

The RNA Revolution in the Central Molecular Biology Dogma Evolution. [PDF]

Int J Mol Sci
Haseltine WA, Patarca R.
europepmc   +1 more source

Structural and molecular biology of Sabiá virus. [PDF]

Exp Biol Med (Maywood), 2023
Bezerra EH, Melo-Hanchuk TD, Marques RE.
europepmc   +1 more source

Proteasome assembly chaperone translation upon stress requires Ede1 phase separation at the plasma membrane

iScience
Summary: Proteome adaptation is key to cells surviving stresses. Increased translation of proteasome assembly chaperones (PACs) is critical for increasing proteasome assembly and cell degradative capacity.
Thomas D. Williams, Aurellia Winaya, Ifeoluwapo Joshua, Adrien Rousseau   +3 more
doaj  

Molecular Biology

, 1969

openalex   +1 more source

Poliomyelitis — epidemiology, molecular biology and immunology [PDF]

, 1982
Philip D. Minor, Olen M. Kew, G. C. Schild   +2 more
openalex   +1 more source